Results 71 to 80 of about 865,703 (290)

The C‐terminal truncated splicing variant of NK1R negatively modulates substance P‐stimulated NK1R signaling

FEBS Open Bio, EarlyView.
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen, Duc Trung Nguyen, Minyoung Cho, Jihun Kim, Soyeon In, Thai Uy Nguyen, Sunghoon Hurh, Beom Jin Park, Jong‐Ik Hwang   +8 more
wiley   +1 more source

Broadcast Cognitive Radio with Dirty Paper Coding over Nakagami-m Fading Channel

Advances in Electrical and Computer Engineering, 2019
The symbol error rate (SER) performance analysis of a broadcast underlay cognitive radio (CR) network, under Nakagami-m fading channels is studied in this paper. Particularly, the underlay CR network is studied as a closed loop multiple antenna system,
BASGUMUS, A., NAMDAR, M., TSIFTSIS, T.
doaj   +1 more source

TRPML1 agonist ML‐SA5 attenuates pulmonary fibroblast activation by suppressing mTOR and restoring autophagic flux

FEBS Open Bio, EarlyView.
TGF‐β1 stimulation downregulates lysosomal channel TRPML1 in pulmonary fibroblasts. The TRPML1 agonist ML‐SA5 suppressed fibroblast‐to‐myofibroblast activation and collagen production. Mechanistically, ML‐SA5 inhibited mTOR phosphorylation, restored autophagic flux, and its effects were enhanced by rapamycin (mTOR inhibitor) and reversed by MHY1485 ...
Jiatong Yao, Xiaoting Kang, Lulu Meng, Shaoxuan Zhang, Qiujie Li, Jinyu Zhou, Mengyue Xue, Chu Li, Hua Zhu, Pengzhou Hang, Jing Zhao   +10 more
wiley   +1 more source

Bit-Error-Rate Analysis of Raptor Codes over Rician Fading Channels

Journal of Electrical and Computer Engineering, 2020
The bit-error-rate expressions of nonsystematic Raptor (NR) codes and systematic Raptor (SR) codes over Rician fading channels are first derived using a Gaussian approximation (GA) approach.
Jingke Dai
doaj   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Slow Frequency-Hopping Multicarrier DS-CDMA for Transmission over Nakagami Multipath Fading Channels

, 2001
A novel multiple access scheme based on slow frequency hopping multicarrier direct-sequence code division multiple access (SFH/MC DS-CDMA) is proposed and investigated, which can be rendered compatible with the existing second-generation narrowband CDMA ...
Yang, L-L., Hanzo, L.
core   +1 more source

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Latency and Networking Aspects of Adaptive Modems over Slow Indoors Rayleigh Fading Channels

, 1999
Adaptive modulation exploits the time-variant channel capacity fluctuation of fading channels using a range of different modem modes. Specifically, no information is transmitted when the instantaneous channel signal-to-noise ratio (SNR) is low, and ...
J.M. Torrance, J. M. Torrance, Torrance, J.M., L. Hanzo, Hanzo, L.   +4 more
core   +2 more sources

Optimizing Utility–Privacy Tradeoff in Federated Learning Over Fading Channels

IEEE Transactions on Machine Learning in Communications and Networking
This paper develops a utility-privacy optimized federated learning (FL) framework that aggregates local updates transmitted over fading channels using only channel state information at the receiver (CSIR).
Yujia Mu, Xizixiang Wei, Yonina C. Eldar, Cong Shen   +3 more
doaj   +1 more source

The Slashed‐Rayleigh Fading Channel Distribution

Mathematical Problems in Engineering, 2019
We propose an alternative distribution for modelling fading‐shadowing wireless channels. This distribution presents certain advantages over the Rayleigh‐lognormal distribution and the K distribution and has proved useful in the setting described. We obtain closed‐form expressions for the average channel capacity and for the average bit error rate of ...
E. Gómez-Déniz, L. Gómez, H. W. Gómez   +2 more
openaire   +3 more sources