Results 11 to 20 of about 15,628 (311)

P-1973. Signal Detection of Neurotoxicity Associated with Carbapenem Use: A FAERS-Based Disproportionality Analysis [PDF]

Open Forum Infect Dis
Linta Susan Kuriakose, Albin Sebastian, Alvin Sunny   +2 more
europepmc   +2 more sources

Fluoroquinolone-Associated Psychiatric and Ocular Adverse Events: A Disproportionality Analysis Using Real-World Data From FAERS (2011-2024). [PDF]

Pharmacol Res Perspect
This pharmacovigilance study identifies a wide range of rapid‐onset neuropsychiatric and ocular adverse effects linked to fluoroquinolones (FQ). Disproportionality analysis revealed a disproportionate reporting of suicidal ideation and visual impairment following FQ treatment, emphasizing the urgent need for cautious prescribing and strengthened safety
Chau HT, Au NPB.
europepmc   +2 more sources

Mifepristone Adverse Events Identified by Planned Parenthood in 2009 and 2010 Compared to Those in the FDA Adverse Event Reporting System and Those Obtained Through the Freedom of Information Act

Health Services Research & Managerial Epidemiology, 2021
Background As part of the accelerated approval of mifepristone as an abortifacient in 2000, the Food and Drug Administration (FDA) required prescribers to report all serious adverse events (AEs) to the manufacturer who was required to report them to the ...
Christina A. Cirucci, Kathi A. Aultman, Donna J. Harrison   +2 more
doaj   +1 more source

Population scale data reveals the antidepressant effects of ketamine and other therapeutics approved for non-psychiatric indications. [PDF]

, 2017
Current therapeutic approaches to depression fail for millions of patients due to lag in clinical response and non-adherence. Here we provide new support for the antidepressant effect of an anesthetic drug, ketamine, by Inverse-Frequency Analysis of ...
Abagyan, Ruben, Atayee, Rabia, Cohen, Isaac V, Makunts, Tigran   +3 more
core   +2 more sources

Analysis of anticholinergic adverse effects using two large databases: The US Food and Drug Administration Adverse Event Reporting System database and the Japanese Adverse Drug Event Report database.

PLoS ONE, 2021
IntroductionAnticholinergic adverse effects (AEs) are a problem for elderly people. This study aimed to answer the following questions. First, is an analysis of anticholinergic AEs using spontaneous adverse drug event databases possible?
Junko Nagai, Yoichi Ishikawa
doaj   +1 more source

Assessing the 2004-2018 fentanyl misusing issues reported to an international range of adverse reporting systems [PDF]

, 2019
© 2019 Schifano, Chiappini, Corkery and Guirguis. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY).
Chiappini, Stephania, Corkery, John, Guirguis, Amira, Schifano, Fabrizio   +3 more
core   +4 more sources

Assessing Cancer Signal during Oral Antiplatelet Therapy in the Food and Drug Administration Adverse Event Reporting System: Mission Impossible

TH Open, 2018
Whether aggressive prolonged dual antiplatelet therapy (DAPT) promotes solid cancer risks remains a critical unsolved issue. Since the evidence from randomized trials, affiliated U.S.
Victor Serebruany, Moo Hyun Kim, Christian Thevathasan, Thomas Marciniak   +3 more
doaj   +1 more source

Mining Frequency of Drug Side Effects Over a Large Twitter Dataset Using Apache Spark [PDF]

, 2017
Despite clinical trials by pharmaceutical companies as well as current FDA reporting systems, there are still drug side effects that have not been caught. To find a larger sample of reports, a possible way is to mine online social media. With its current
Hsu, Dennis
core   +3 more sources

A Real-World Disproportionality Analysis of Olaparib: Data Mining of the Public Version of FDA Adverse Event Reporting System

Clinical Epidemiology, 2022
Yamin Shu,1 Xucheng He,2 Yanxin Liu,3 Pan Wu,4 Qilin Zhang5 1Department of Pharmacy, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China; 2Department of Pharmacy, Pengzhou Second ...
Shu Y, He X, Liu Y, Wu P, Zhang Q
doaj  

Seeking out non-public information : sell-side analysts and the freedom of information act [PDF]

, 2019
A number of sell-side healthcare analysts gain access to information outside the purview of management through Freedom of Information Act requests to the Food and Drug Administration for records on factory inspections, complaints, and drug and medical ...
Klein, April, Li, Tao, Zhang, Bobo
core   +1 more source