Results 61 to 70 of about 15,628 (311)

Unravelling the Major Cardiovascular Risks of Systemic Psoriasis Medications: A Literature Systematic Review

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Psoriasis is a chronic inflammatory dermatological condition associated with an elevated risk of cardiovascular events (CVEs). Systemic therapies have transformed disease management, but their cardiovascular (CV) safety profiles remain incompletely understood and inconsistently reported.
Mai Thi Hoai Son, Yves Julien Mbama Biloa, Pauline Gouttefarde, Thomas Franck, Gilles Cizeron, Mathieu Oriol, François Maccari, Elisa Cinotti, Beatrice Trombert‐Paviot, Bienvenu Bongue, Jean‐Luc Perrot   +10 more
wiley   +1 more source

Adverse event reports in patients taking psychiatric medication during pregnancy from spontaneous reports in Japan and the United States: an approach using latent class analysis

BMC Psychiatry, 2020
Background Little is known regarding the association between adverse events (AEs) and psychiatric medications administered to pregnant women in clinical trials during the pre-marketing period.
Tatsuhiko Anzai, Kunihiko Takahashi, Michiko Watanabe, Mayumi Mochizuki, Atsuko Murashima   +4 more
doaj   +1 more source

Mining directional drug interaction effects on myopathy using the FAERS database [PDF]

, 2018
Mining high-order drug-drug interaction (DDI) induced adverse drug effects from electronic health record (EHR) databases is an emerging area, and very few studies have explored the relationships between high-order drug combinations.
Chasioti, Danai, Lerner, Samuel, Li, Lang, Ning, Xia, Quinney, Sara K., Shen, Li, Yao, Xiaohui, Zhang, Pengyue   +7 more
core   +1 more source

The real-world safety profile of tirzepatide: pharmacovigilance analysis of the FDA Adverse Event Reporting System (FAERS) database

Journal of Endocrinological Investigation
Randomized controlled trials with tirzepatide (TZP) displayed unprecedented glucose and body weight lowering efficacy in individuals with type 2 diabetes and/or obesity and a safety profile similar to that of glucagon-like peptide-1 receptor agonists ...
I. Caruso, L. Di Gioia, S. Di Molfetta, M. Caporusso, A. Cignarelli, G. P. Sorice, L. Laviola, F. Giorgino   +7 more
semanticscholar   +1 more source

The Evolution of Pneumocystis jirovecii Pneumonia Prophylaxis for Pediatric Patients With Extracranial Solid Tumors: A Review of Historical Insights and Future Directions

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pneumocystis jirovecii pneumonia (PJP) remains a modern‐day complication for pediatric patients receiving treatment for extracranial solid tumors (ST), highlighting the need for reconsideration of our current approach toward PJP prophylaxis. This critical review aims to evaluate both universal and risk‐stratified approaches to PJP prophylaxis ...
Kriti Kumar, Denise M. Connolly, Ellen Kellington, Elyse Zelunka, Karla Kerrigan, Furqan Shaikh, Paul C. Nathan, Meredith S. Irwin, Sarah Cohen‐Gogo   +8 more
wiley   +1 more source

SGLT-2 Inhibitors: A Novel Mechanism in Targeting Glycemic Control in Type 2 Diabetes Mellitus [PDF]

, 2016
OBJECTIVE: To review the chemistry, pharmacology, pharmacodynamics, pharmacokinetics, clinical efficacy, tolerability, dosing, drug interactions, and administration of canagliflozin, dapagliflozin, and empagliflozin, and comparing the benefit and risk ...
Ahmed-Sarwar, Nabila, Nathan, Kobi T, Werner, Paul M   +2 more
core   +2 more sources

Indications and adverse events of teriparatide: based on FDA adverse event reporting system (FAERS)

Frontiers in Pharmacology
Background Teriparatide is approved for osteoporosis. Post-marketing surveillance is critical given its widespread use. Objective To investigate adverse events (AEs) associated with teriparatide using the FAERS database, compare association strengths for
Ming-Tao Wen, Jia-Cheng Li, Bowen Lu, Huarong Shao, Pei-Xue Ling, Fei Liu, Gang Li, Di Luo   +7 more
semanticscholar   +1 more source

Effects of vertical confinement on gelation and sedimentation of colloids [PDF]

, 2017
We consider the sedimentation of a colloidal gel under confinement in the direction of gravity. The confinement allows us to compare directly experiments and computer simulations, for the same system size in the vertical direction.
Fullerton, Christopher J., Hallett, James, Jack, Robert L., Razali, Azaima, Royall, C. Patrick, Turci, Francesco   +5 more
core   +3 more sources

Network medicine and systems pharmacology approaches to predicting adverse drug effects

British Journal of Pharmacology, EarlyView.
Identifying and understanding the relationships between drug intake and adverse effects that can occur due to inadvertent molecular interactions between drugs and targets is a difficult task, especially considering the numerous variables that can influence the onset of such events.
Alessio Funari, Giulia Fiscon, Paola Paci   +2 more
wiley   +1 more source

Drug Safety During Breastfeeding: A Comparative Analysis of FDA Adverse Event Reports and LactMed^®

Pharmaceuticals
Background/Objectives: While breastfeeding is highly recommended, breastfed infants may be exposed to drugs by milk due to maternal pharmacotherapy, resulting in a risk of adverse drug events (ADE) or reactions (ADRs). The U.S.
Hülya Tezel Yalçın, Nadir Yalçın, Michael Ceulemans, Karel Allegaert   +3 more
doaj   +1 more source