Results 81 to 90 of about 9,966 (258)

Studying synthesis confinement effects on the internal structure of nanogels in computer simulations [PDF]

, 2019
We study the effects of droplet finite size on the structure of nanogel particles synthesized by random crosslinking of molecular polymers diluted in nanoemulsions.
Kantorovich, Sofia S., Likos, Christos N., Minina, Elena S., Sánchez, Pedro A.   +3 more
core   +1 more source

Delirium Associations with Antibiotics: A Pharmacovigilance Study of the FDA Adverse Event Reporting System (FAERS) [PDF]

, 2021
Chengwen Teng, Christopher R. Frei
openalex   +1 more source

Limitations of FAERS‐based analyses of paternal drug exposure: The critical need for maternal data integration

Andrology, EarlyView.
Mikako Goto, Izumi Fujioka, Yasuha Ogawa, Sachi Koinuma, Koushi Yamaguchi   +4 more
wiley   +1 more source

Identifying Pediatric Drug Safety Knowledge Gaps: An Integrated Approach Leveraging Real‐World Data, a Biomedical Knowledge Base, and Postmarketing Surveillance Data

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 45, Issue 10, Page 667-676, October 2025.
ABSTRACT Background Drug safety has historically been understudied in pediatric populations, rendering them “therapeutic orphans.” Pediatric drug indications and dosages are often inferred by extrapolating safety, efficacy, and dosing data from adult studies, leading to widespread off‐label use.
Saurabh Rahurkar, Jiayi Ouyang, Pallavi Jonnalagadda, Xiaofu Liu, Shijun Zhang, Chien‐Wei Chiang, Lei Wang, Aditi Shendre, Lang Li   +8 more
wiley   +1 more source

Safety of lifitegrast: A real-world pharmacovigilance study based on FAERS

PLOS One
To comprehensively assess the safety of Lifitegrast, a drug for dry eye disease, we conducted a comprehensive analysis of adverse event (AE) reports from the FDA Adverse Event Reporting System (FAERS). This retrospective study examined all AE reports submitted between Q3 2016 and Q2 2024, employing disproportionality analysis to identify safety signals
Chu Zhang, Hui Wang, Xianglei Chen, Yong Liu, Puen Jiang   +4 more
openaire   +3 more sources

Safety analysis of quinolones use in minors—based on the FAERS database

Frontiers in Medicine
ObjectiveThis study utilizes the FDA Adverse Event Reporting System (FAERS) to investigate adverse drug event (ADE) signals linked to quinolones use (ciprofloxacin, moxifloxacin, levofloxacin, ofloxacin) in minors, offering insights for clinical use.MethodsMinors were categorized into four age groups.
Yanwei Li, Jing Wang, ChengLiang Wang, Li Chen, Li Chen, Li Chen   +5 more
openaire   +3 more sources

Safety assessment of sapropterin dihydrochloride: real-world adverse event analysis based on the FDA adverse event reporting system (FAERS)

Frontiers in Pharmacology
ObjectiveSapropterin dihydrochloride is the first drug for the therapy of phenylketonuria, which is a rare disease that occurs one of 10,000–15,000 newborns.
Jiahong Zhong, Xihui Yu, Zhuomiao Lin
doaj   +1 more source

Concordance and predictive value of two adverse drug event data sets [PDF]

, 2014
Background: Accurate prediction of adverse drug events (ADEs) is an important means of controlling and reducing drug-related morbidity and mortality.
Cami, Aurel, Reis, Ben Y
core   +1 more source

Evaluation of Rivaroxaban- and Dabigatran-Associated Hemorrhagic Events Using the FDA-Adverse Event Reporting System Database (FAERS) [PDF]

, 2021
Mingxing Guo, Sydney Thai, Junwen Zhou, Jingkai Wei, Ying Zhao, Wanyi Xu, Tiansheng Wang, Xiangli Cui   +7 more
openalex   +1 more source

Detection and analysis of the safety profile of talazoparib based on FAERS database

Expert Opinion on Drug Safety
Talazoparib was approved for the treatment of breast cancer. However, the safety of talazoparib in a large population sample over an extended period remained uncertain. The objective of this study is to offer guidance for the secure utilization of talazoparib in clinical settings.
Mufei Tang, Peiyan Liu, Linzhe Du, Yuanyuan Li, Jinjin Chen, Yang Li   +5 more
openaire   +2 more sources