Results 131 to 140 of about 1,661,739 (261)
LABOUR INDUCTION WITH ORAL MISOPROSTOL IN PRE LABOUR RUPTURE OF MEMBRANES AT TERM
Journal of University Medical & Dental College, 2013 Objective: To assess the efficacy of oral misoprostol for induction of labour in women with pre labour rupture of membranes at term and to monitor maternal and fetal complications.
Umber Fatima, Mubashra Naz
doaj
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Failed double-blind replication of offline 5Hz-rTUS-induced corticospinal excitability
Failed replication of the Zeng et al., (2022) study titled 'Induction of Human Motor Cortex Plasticity by Theta Burst Transcranial Ultrasound Stimulation'
Po-Yu Fong +4 more
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Induction Experiences of Beginning Secondary Teachers in Solomon Islands [PDF]
, 2011 Research shows teacher induction programmes are crucial in supporting new teachers as they move into the profession. Widely implemented in different ways in many countries they have a shared purpose, which is to provide beginning teachers with an ...
Bosamata, James
core
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Introduction: Induction of labor is more frequently used obstetric procedure, practiced in over 20% of pregnancies globally, with 20% resulting in cesarean delivery. Worldwide, unsuccessful induction of labor is a public health concern.
HABEN NIGUSE
core +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source