Results 111 to 120 of about 1,661,739 (261)

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

The Pessimistic Induction: A Bad Argument Gone Too Far [PDF]

, 2012
In this paper, I consider the pessimistic induction construed as a deductive argument (specifically, reductio ad absurdum) and as an inductive argument (specifically, inductive generalization).
Mizrahi, Moti
core  

Induction of Labor After Fetal Demise in Third Trimester—A Retrospective Cohort Study

Clinics and Practice
Objectives: The aim of our study was to assess the efficacy and safety of two different labor induction methods in patients after fetal demise beyond 28 weeks, with an unfavorable cervix: misoprostol—prostaglandin E1 analog (PGE1) and dinoprostone ...
Sara Vodopivec, Gorazd Kavšek, Polona Pečlin, Mirjam Druškovič   +3 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Implementation Of New Definitions Of Labor Arrest Disorders And Failed Induction Can Decrease The Cesarean Rate [PDF]

, 2018
Cesarean delivery for labor arrest currently makes up the largest proportion of primary cesarean delivery in the United States. Because cesarean delivery is associated with significant morbidity, it is important to limit its use to ensure the benefits ...
Greenberg, Jessica Tanzer Wright
core   +1 more source

Failed induction of labor and associated factors among women undergoing induction of labor

International Journal of Reproduction, Contraception, Obstetrics and Gynecology
Background: Induction of labor (IOL) is increasingly employed in modern obstetric care, yet carries a significant risk of failure, contributing to higher caesarean rates and associated maternal-neonatal morbidity. Identifying factors that influence IOL success is essential for individualized labor management.
Gayatri L. Patil, Tejaswi V. Pujar, Pooja Hombardi, Veda R.   +3 more
openaire   +1 more source

Mitochondria are positioned at dendritic branch induction sites, a process requiring rhotekin2 and syndapin I

Nature Communications
Proper neuronal development, function and survival critically rely on mitochondrial functions. Yet, how developing neurons ensure spatiotemporal distribution of mitochondria during expansion of their dendritic arbor remained unclear.
Jessica Tröger, Regina Dahlhaus, Anne Bayrhammer, Dennis Koch, Michael M. Kessels, Britta Qualmann   +5 more
doaj   +1 more source

Risk factors for failed induction of labor: A retrospective study in a single, tertiary, perinatal-care center

Taiwanese Journal of Obstetrics & Gynecology
Objective: To estimate the incidence and associated risk factors of failed induction of labor (IOL). Materials and methods: A retrospective, case–control study was conducted on a cohort of women who underwent IOL from January 2020 to December 2023 and ...
Maika Nariai, Osamu Wada-Hiraike, Takayuki Iriyama, Takahiro Seyama, Keiichi Kumasawa, Yasushi Hirota, Yutaka Osuga   +6 more
doaj   +1 more source

Logic of Induction: A Dead Horse? Some Thoughts on the Logical Foundations of Probability [PDF]

Princípios, 2007
Our purpose in this paper is twofold. The first is to understand why Carnap´s project of building a logic of induction as a whole was not successful.
Ricardo Sousa Silvestre
doaj  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source