Results 141 to 150 of about 11,498,837 (391)

2024 update in heart failure

ESC Heart Failure
In the last years, major progress has occurred in heart failure (HF) management. The 2023 ESC focused update of the 2021 HF guidelines introduced new key recommendations based on the results of the last years of science.
Alberto Beghini, A. Sammartino, Z. Papp, Stephan von Haehling, J. Biegus, P. Ponikowski, M. Adamo, L. Falco, C. M. Lombardi, M. Pagnesi, G. Savarese, M. Metra, D. Tomasoni   +12 more
semanticscholar   +1 more source

Successful bone marrow transplantation in a patient with DNA ligase IV deficiency and bone marrow failure [PDF]

, 2007
Bernd Gruhn, J. Seidel, F Zintl, Raymonda Varon, Holger Tönnies, Heidemarie Neitzel, Astrid Bechtold, Holger Hoehn, Detlev Schindler   +8 more
openalex   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Prognostic Value of Biomarkers in Heart Failure [PDF]

, 2009
Shannon M. Dunlay, Yariv Gerber, Susan A. Weston, Jill M. Killian, Margaret M. Redfield, Véronique L. Roger   +5 more
openalex   +1 more source

Tumor and germline testing with next generation sequencing in epithelial ovarian cancer: a prospective paired comparison using an 18‐gene panel

Molecular Oncology, EarlyView.
Genetic testing in epithelial ovarian cancer includes both germline and tumor‐testing. This approach often duplicates resources. The current prospective study assessed the feasibility of tumor‐first multigene testing by comparing tumor tissue with germline testing of peripheral blood using an 18‐gene NGS panel in 106 patients.
Elisabeth Spenard, Cristina Mitric, Melanie Care, Tracy L. Stockley, Raymond H. Kim, Jeanna McCuaig, Blaise Clarke, Laura Ranich, Clare Sheen, Sarah E. Ferguson, Liat Hogen, Taymaa May, Marcus Q. Bernardini   +12 more
wiley   +1 more source

The usefulness of His bundle pacing in a heterogeneous population of patients with impaired left ventricular systolic function

Cardiology Journal
BACKGROUND: His bundle pacing (HBP) maintains a physiological activation pattern of ventricular activation, and in patients with intraventricular conduction delay (IVCD) it can normalize wide QRS duration.
Rafal Gardas, Krzysztof S. Golba, Danuta Loboda, Jolanta Biernat, Tomasz Soral, Piotr Kulesza, Mateusz Sajdok, Kamil Zub   +7 more
doaj   +1 more source

Second law of thermodynamics and the failure of rock materials [PDF]

, 2001
The relation of nonequilibrium thermodynamics to some failure and fracture theories of rock mechanics is investigated. The basic concepts are given to connect failure to the properties of material equations describing the elastic properties.
Ván, Péter, Vásárhelyi, Balázs
core  

Advancing Dynamic Fault Tree Analysis

, 2016
This paper presents a new state space generation approach for dynamic fault trees (DFTs) together with a technique to synthesise failures rates in DFTs. Our state space generation technique aggressively exploits the DFT structure --- detecting symmetries,
Junges, Sebastian, Katoen, Joost-Pieter, Volk, Matthias   +2 more
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

Molecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang, Qian Sun, Daniel Novak, Lei Zhu, Juliane Poelchen, Tamara Steinfass, Yiman Wang, Viktor Umansky, Jochen Utikal   +8 more
wiley   +1 more source

Revascularization for Controlling Hypertension and Improving Cardiorenal Failure in Leriche Syndrome [PDF]

, 2022
Sho Takagi, Keisuke Hirano, Akio Nakasu, Junji Yanagisawa, Yoshihiro Goto, Yasuhide Okawa   +5 more
openalex   +1 more source