Results 41 to 50 of about 8,833,991 (337)

Implementing Health‐Related Quality of Life Assessment in Pediatric Oncology: A Feasibility Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background There is growing interest in embedding health‐related quality of life (HRQoL) assessment and patient‐reported outcome measures (PROMs) within clinical cancer care. This study evaluated the feasibility, acceptability, and usability of implementing an electronic PROM (ePROM) platform to measure HRQoL in children with cancer ...
Mikaela Doig, Sophie Jessop, Jordan R. Hansford, Hien Le, Matthew O'Connor, Peter Gorayski, Andrew Cunningham, Amanda Hutchinson, Victoria Bedford, Eva Bezak, Nayana Parange, Kelly Skelton, Timothy Price, Michala Short   +13 more
wiley   +1 more source

A new approach to characterize cardiac sodium storage by combining fluorescence photometry and magnetic resonance imaging in small animal research

Scientific Reports
Cardiac myocyte sodium (Na+) homoeostasis is pivotal in cardiac diseases and heart failure. Intracellular Na+ ([Na+]i) is an important regulator of excitation–contraction coupling and mitochondrial energetics.
Martin Christa, Franziska Dithmar, Tobias Weinaus, Michael Kohlhaas, Anahi-Paula Arias-Loza, Michelle Hofmann, Ibrahim A. Elabyad, Fabian T. Gutjahr, Christoph Maack, Wolfgang R. Bauer   +9 more
doaj   +1 more source

Transient heart rate reduction improves acute decompensated heart failure‐induced left ventricular and coronary dysfunction

ESC Heart Failure, 2021
Aims Acute decompensated heart failure (ADHF), a live‐threatening complication of heart failure (HF), associates a further decrease of the already by HF‐impaired cardiac function with an increase in heart rate.
Nicolas Peschanski, Najah Harouki, Matthieu Soulie, Marianne Lachaux, Lionel Nicol, Isabelle Remy‐Jouet, Jean‐Paul Henry, Anais Dumesnil, Sylvanie Renet, Françoise Fougerousse, Ebba Brakenhielm, Antoine Ouvrard‐Pascaud, Christian Thuillez, Vincent Richard, Jérôme Roussel, Paul Mulder   +15 more
doaj   +1 more source

Benefit of viral load testing for confirmation of immunological failure in HIV patients treated in rural Malawi. [PDF]

, 2011
Objective  Viral load testing is used in the HIV programme of Chiradzulu, Malawi, to confirm the diagnosis of immunological failure to prevent unnecessary switching to second-line therapy.
Badri, Bisson, Calmy, Ekouevi, Ferradini, Kantor, Keiser, Lebon, Mee, Moore, Murri, Reynolds, van Oosterhout, World Health Organization, World Health Organization   +14 more
core   +2 more sources

Rapid Response to Trametinib Combined With Chemotherapy for Infant BRAF‐Fused Chiasmatic Glioma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Infants, less than 1 year, with chiasmatic gliomas (ICG) present a major therapeutic challenge due to large tumor size, decreased vision, rapid progression, and poor response to vincristine/carboplatin chemotherapy. The majority have a BRAF fusion, which may respond to downstream MEK inhibitors but response time is slow. There are no safety or
Helen Toledano, Alexander Yelak, Walid Kaadan, Shlomo Caduri, Rivka Friedland, Orli Michaeli, Gad Dotan, Osnat Konen   +7 more
wiley   +1 more source

Single Center Experience With Impella 5.5 for Escalation and De-Escalation of Cardiogenic Shock Patients

Journal of Interventional Cardiology
Temporary mechanical circulatory support (tMCS) devices are a critical component for treating patients with cardiogenic shock (CS). We analyzed use of Impella 5.5 device for efficacy and safety in a single-center CS population from February 2022 and ...
Ioana Dumitru, Debbie Rinde-Hoffman, Maria Sevillano, Leeandra Schnell, Elizabeth Quintilliani, Swaroop Bommareddi   +5 more
doaj   +1 more source

Heart failure in patients with coronary heart disease: Prevalence, characteristics and guideline implementation – Results from the German EuroAspire IV cohort

BMC Cardiovascular Disorders, 2017
Background Adherence to pharmacotherapeutic treatment guidelines in patients with heart failure (HF) is of major prognostic importance, but thorough implementation of guidelines in routine care remains insufficient.
Caroline Morbach, Martin Wagner, Stefan Güntner, Carolin Malsch, Mehmet Oezkur, David Wood, Kornelia Kotseva, Rainer Leyh, Georg Ertl, Wolfgang Karmann, Peter U Heuschmann, Stefan Störk   +11 more
doaj   +1 more source

Association between the Length of Hospital Stay and 30-Day Outcomes in Patients Admitted with Acute Decompensated Heart Failure

Emergency Medicine International, 2023
Background and Aim. Regarding patients admitted with acute decompensated heart failure (ADHF), there are inconsistent reports surrounding the association between length of stay (LOS) and mortality or rehospitalization following discharge.
Melika Namvar, Mohammad Fakhrolmobasheri, Sadegh Mazaheri-Tehrani, Maryam Heidarpour, Maryam Emamimeybodi, Davood Shafie   +5 more
doaj   +1 more source

A PRSZT Registry Analysis of Prognostic Factors Influencing Survival and Relapse Rates After Second Allogeneic Hematopoietic Stem Cell Transplantation in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A second allogeneic (allo‐)hematopoietic stem cell transplantation (HSCT2) is a potential curative option for pediatric patients with acute lymphoblastic leukemia (ALL) following relapse after first allogeneic transplantation (HSCT1), but its efficacy is limited by high relapse rates and transplant‐related toxicity in highly pretreated ...
Ava Momm, Imme Haubitz, Rita Beier, Martin Zimmermann, Andrej Lissat, Peter Bader, Matthias Eyrich, Jan‐Henning Klusmann, Matthias Wölfl, Paul‐Gerhardt Schlegel, Verena Wiegering   +10 more
wiley   +1 more source

Weight Loss in Obese Patients With Heart Failure

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016
BackgroundIn heart failure (HF), weight loss (WL) has been associated with an adverse prognosis whereas obesity has been linked to lower mortality (the obesity paradox). The impact of WL in obese patients with HF is incompletely understood. Our objective
Elisabet Zamora, Carles Díez‐López, Josep Lupón, Marta de Antonio, Mar Domingo, Javier Santesmases, María Isabel Troya, Crisanto Díez‐Quevedo, Salvador Altimir, Antoni Bayes‐Genis   +9 more
doaj   +1 more source