Results 51 to 60 of about 2,766,558 (268)

Circular RNA circBNC2 inhibits epithelial cell G2-M arrest to prevent fibrotic maladaptive repair

Nature Communications, 2022
G2/M arrest of epithelial cells leads to fibrosis with unclear mechanisms. This study identifies a protein-encoding circRNA, circBNC2, which inhibits epithelial cells G2/M arrest to prevent fibrotic maladaptive repair in damaged kidney and liver ...
Peng Wang, Zhitao Huang, Yili Peng, Hongwei Li, Tong Lin, Yingyu Zhao, Zheng Hu, Zhanmei Zhou, Weijie Zhou, Youhua Liu, Fan Fan Hou   +10 more
doaj   +1 more source

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source

Failure detectors in omission failure environments [PDF]

Proceedings of the sixteenth annual ACM symposium on Principles of distributed computing - PODC '97, 1997
We study failure detectors in an asynchronous environment that admits message omission failures. In such environments, processes may fail by crashing, but may also {\em disconnect\/} from each other. We adapt Chandra and Toueg''s definitions of failure detection completeness and accuracy to the omissions failure model, and define a weak failure ...
Dolev, Danny, Friedman, Roy, Keidar, Idit, Malkhi, Dahlia   +3 more
openaire   +1 more source

Acute Heart Failure as a First Manifestation of Primary Adrenal Insufficiency: Highly Lethal If Not Diagnosed!

Case Reports in Endocrinology
Background. Primary adrenal insufficiency is an uncommon condition that manifests as nonspecific symptoms such as fatigue, weight loss, salt craving, and hyperpigmentation.
Maryam Heidarpour, Mohammad Mehdi Zare, Shiva Armani, Hedie Torkashvan, Sadegh Mazaheri-Tehrani, Davood Shafie   +5 more
doaj   +1 more source

Insuficiencia cardíaca descompensada en un solo centro de un país latinoamericano: hallazgos de los primeros 1595 casos en el registro ICARUS

Archivos de Cardiología de México
Objetivo: Describir los aspectos metodológicos, las características sociodemográficas y clínicas de los pacientes hospitalizados con ICAD y sus desenlaces a corto plazo.
Lyda Z. Rojas, Sergio A. Gómez-Ochoa, Jaime A. Rodríguez, Karen A. García-Rueda, Angela M. Torres-Bustamante, Daniel R. Botero, María Cantillo-Reines, Angie Y. Serrano-García, Adriana M. Jurado, Kelly J. Castro, Katerine Pinilla, Angie C. Mendoza-Quiñonez, Nelly J. Vasquez, Yeinmy Y. Alvarez, Maribel Rojas, Diana M. Ortega-Solano, Yesenia Sanabria, Angelica Vargas-Sanabria, Aura M. Cáceres, Paula S. Bohorquez-Hernández, Carlos Portillo, Luis E. Echeverria   +21 more
doaj   +1 more source

Transient heart rate reduction improves acute decompensated heart failure‐induced left ventricular and coronary dysfunction

ESC Heart Failure, 2021
Aims Acute decompensated heart failure (ADHF), a live‐threatening complication of heart failure (HF), associates a further decrease of the already by HF‐impaired cardiac function with an increase in heart rate.
Nicolas Peschanski, Najah Harouki, Matthieu Soulie, Marianne Lachaux, Lionel Nicol, Isabelle Remy‐Jouet, Jean‐Paul Henry, Anais Dumesnil, Sylvanie Renet, Françoise Fougerousse, Ebba Brakenhielm, Antoine Ouvrard‐Pascaud, Christian Thuillez, Vincent Richard, Jérôme Roussel, Paul Mulder   +15 more
doaj   +1 more source

An [Imperfect] Case for Dyadic Research in Pediatric Psychosocial Oncology

Pediatric Blood &Cancer, EarlyView.
Stephanie M. Nanos, Lindsay A. Jibb, Gary Rodin   +2 more
wiley   +1 more source

Admixture Mapping Reveals Candidate Regions for Methotrexate Neurotoxicity Susceptibility: A Reducing Disparities in Acute Leukemia Consortium Report

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Neurotoxicity is a rare, often dose‐limiting adverse effect of methotrexate (MTX) therapy that disproportionally affects Latino children. Factors contributing to the observed disparity are not well understood. This study leveraged admixture mapping to identify genetic regions associated with MTX‐related neurotoxicity susceptibility ...
Rachel D. Harris, Priya B. Shetty, Olga A. Taylor, Elizabeth G. Atkinson, Melissa A. Richard, M. Monica Gramatges, Mark Zobeck, Sandi Pruitt, Amy Hughes, M. Brooke Bernhardt, Ashley Chavana, Van Huynh, Kathleen Ludwig, Laura Klesse, Kenneth Heym, Timothy Griffin, Rodrigo Erana, Juan Carlos Bernini, Han Chen, Bing Yu, Philip J. Lupo, Karen R. Rabin, Michael E. Scheurer, Austin L. Brown, The REDIAL Consortium   +24 more
wiley   +1 more source

Potentiostatic threshold potentials of stainless steels [PDF]

E3S Web of Conferences, 2019
Potentiodynamic measurements are used to determine key potentials to classify certain corrosion properties. The material selection for components (e.g. shafts) in corrosive environments is widely based upon these potentiodynamic measurements.
Mehlich Martin, Hoffmeister Hans, Böllinghaus Thomas, Münster Christoph   +3 more
doaj   +1 more source

Impact of Metastatic Patterns on Survival and Response to Therapy in Neuroblastoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background While the presence of metastases in neuroblastoma (NB) is a well‐established prognostic factor, the clinical significance of dissemination patterns and tumour burden and their impact on response and survival remains poorly understood.
Mariona Morell‐Daniel, Santiago Pérez‐Hoyos, Aroa Soriano, Ana Coma, Amalia Varo, Raquel Hladun, Gabriela Guillén, Soraya Mico, Marta Garrido, Lourdes Rubio, Alba Rubio‐San‐Simón, Ana Minguez, Ricardo López‐Almaraz, Laura Illade, Miguel F. Segura, Lucas Moreno   +15 more
wiley   +1 more source