Results 71 to 80 of about 2,766,558 (268)

Integrated proteomic and metabolomic profiling reveals novel insights on the inflammation and immune response in HFpEF

BMC Genomics
Background The precise mechanisms leading to the development of heart failure with preserved ejection fraction (HFpEF) remain incompletely defined. In this study, an integrative approach utilizing untargeted proteomics and metabolomics was employed to ...
Muyashaer Abudurexiti, Refukaiti Abuduhalike, Tuersunjiang Naman, Nuerdun Wupuer, Dongqin Duan, Mayire Keranmu, Ailiman Mahemuti   +6 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

The failure of failures in a paradigm for asynchronous communication [PDF]

, 1991
We develop a general framework for a variety of concurrent languages all based on asynchronous communication, like data flow, concurrent logic, concurrent constraint languages and CSP with asynchronous channels. The main characteristic of these languages is that processes interact by reading and modifying the state of some common data structure.
Frank S. de Boer, Joost N. Kok, Catuscia Palamidessi, Jan J. M. M. Rutten   +3 more
openaire   +1 more source

Sepsis severity in chronic intestinal failure patients presenting with catheter related blood stream infection

Intestinal Failure
Introduction: The occurrence of catheter related blood stream infection (CRBSI) is a leading cause of morbidity and mortality for patients receiving home parenteral support (HPS) via a central venous catheter (CVC), as part of their chronic intestinal ...
Ashley Bond, Maja Kopczynska, Antje Teubner, Arun Abraham, Jaclyn Salt, Maria Barrett, Simon Lal   +6 more
doaj   +1 more source

Post-Transcriptional Regulation of Hepatic DDAH1 with TNF Blockade Leads to Improved eNOS Function and Reduced Portal Pressure In Cirrhotic Rats

Scientific Reports, 2017
Portal hypertension (PH) is a major cause of morbidity and mortality in chronic liver disease. Infection and inflammation play a role in potentiating PH and pro-inflammatory cytokines, including TNF, are associated with severity of PH.
V. Balasubramanian, G. Mehta, H. Jones, V. Sharma, N. A. Davies, R. Jalan, R. P. Mookerjee   +6 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The Failure to Examine Failures in Democratic Innovation

Political Science and Politics, 2017
While empirical research on democratic innovations is characterised by steady growth in output, a study of the top journals in political science shows that in the last ten years the vast majority of these empirical studies focused on best practices. Empirical evaluation of the lessons that we can draw from failures in participatory and deliberative ...
Spada, Paolo, Ryan, Matt
openaire   +3 more sources

Prognostic Impact of Baseline Potassium Abnormalities in Patients with Heart Failure with Reduced Ejection Fraction: A Real-World Cohort Study

Medical Sciences
Introduction: Abnormal serum potassium levels are a common issue in patients with heart failure with reduced ejection fraction (HFrEF), limiting the use of prognostically beneficial therapies.
Alvaro Roldan-Guerra, Jorge Perea-Armijo, Rafael González-Manzanares, Juan Carlos Castillo-Domínguez, Manuel Crespin-Crespin, Manuel Pan-Álvarez Ossorio, Manuel Anguita-Sánchez, José López-Aguilera   +7 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Correction: The role of RIPK1 mediated cell death in acute on chronic liver failure

Cell Death and Disease, 2022
Takayuki Kondo, Stewart Macdonald, Cornelius Engelmann, Abeba Habtesion, Jane Macnaughtan, Gautam Mehta, Rajeshwar P. Mookerjee, Nathan Davies, Marco Pavesi, Richard Moreau, Paolo Angeli, Vicente Arroyo, Fausto Andreola, Rajiv Jalan   +13 more
doaj   +1 more source