Results 81 to 90 of about 2,757,263 (268)
The failure of failures in a paradigm for asynchronous communication [PDF]
We develop a general framework for a variety of concurrent languages all based on asynchronous communication, like data flow, concurrent logic, concurrent constraint languages and CSP with asynchronous channels. The main characteristic of these languages is that processes interact by reading and modifying the state of some common data structure.
Frank S. de Boer +3 more
openaire +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The role of the gut microbiome in sex differences in arterial pressure
There has been intense interest in the role of the gut microbiome in human health and a broad range of diseases in recent years. In the context of cardiovascular disease, gut dysbiosis (defined as a change in the gut microbiome and the gut-epithelial ...
Anna L. Beale +2 more
doaj +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Failure to Rescue, Failure to Respond
Bromberger, Bianca, Nguyen, Tom C.
openaire +2 more sources
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Knowledge about a patient’s physical fitness can aid in medical decision-making, but objective assessment can be challenging and time-consuming. We aimed to investigate the concordance of self-reported health status and physical functioning with the 6 ...
Nicola Moser +9 more
doaj +1 more source
The Failure Of Defining Failure
Despite the widespread use of the terms 'failure' and 'success' within social networking site (SNS) literature, determining benchmarks of either is a complex undertaking. Success and failure both are often identified according to the presence or absence of context-specific 'markers.' 'Snapshot' metrics such as network growth or activity are pointed ...
Erika Pearson, Adon Moskal
openaire +2 more sources

