Results 81 to 90 of about 4,569,825 (258)
Guoji laonian yixue zazhi[Objective] To investigate the correlation of mitochondrial DNA copy number (mtDNAcn), Klotho protein, myostatin (MSTN) and their combination with physical frailty in elderly patients with sarcopenia.
Zhou Yanyan +5 more
doaj +1 more source
Using Data-Driven Prognostic Algorithms for Completing Independent Failure Analysis
, 2011 ITC/USA 2011 Conference Proceedings / The Forty-Seventh Annual International Telemetering Conference and Technical Exhibition / October 24-27, 2011 / Bally's Las Vegas, Las Vegas, NevadaCurrent failure analysis practices use diagnostic technology ...
Losik, Len
core +4 more sources
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
BMC GenomicsBackground The precise mechanisms leading to the development of heart failure with preserved ejection fraction (HFpEF) remain incompletely defined. In this study, an integrative approach utilizing untargeted proteomics and metabolomics was employed to ...
Muyashaer Abudurexiti +6 more
doaj +1 more source
High‐Sensitivity Troponin: A Clinical Blood Biomarker for Staging Cardiomyopathy in Fabry Disease
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2016 BackgroundHigh‐sensitivity troponin (hs‐TNT), a biomarker of myocardial damage, might be useful for assessing fibrosis in Fabry cardiomyopathy. We performed a prospective analysis of hs‐TNT as a biomarker for myocardial changes in Fabry patients and a ...
Nora Seydelmann +11 more
doaj +1 more source
Multiscale Failure Analysis of Fiber Reinforced Concrete based on continuum and discrete models
, 2011 Fiber inclusions lead to significant improvements of post-cracking behavior of mortar composites by bridging cracks and providing resistance to crack opening processes.
Caggiano A, Etse G, Vrech S
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Intestinal FailureIntroduction: The occurrence of catheter related blood stream infection (CRBSI) is a leading cause of morbidity and mortality for patients receiving home parenteral support (HPS) via a central venous catheter (CVC), as part of their chronic intestinal ...
Ashley Bond +6 more
doaj +1 more source
, 2017 This article refers to 'Prevention of the development of heart failure with preserved ejection fraction by the phosphodiesterase-5A inhibitor vardenafil in rats with type 2 diabetes,' by C.Matyas et al., published in this issue on pages 326 ...
Paulus, Walter J. +8 more
core +1 more source