Results 101 to 110 of about 15,405,604 (296)

Experimental analyses by SIMMER-III on duct-wall failure and fuel discharge/relocation behavior

Mechanical Engineering Journal, 2014
This paper describes experimental analyses using SIMMER-III and -IV, which are respectively two- and three-dimensional multi-component multi-phase Eulerian fluid-dynamics codes, for the purpose of integral code validation.
Hidemasa YAMANO, Yoshiharu TOBITA
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Failure Behavior of Aluminum Solar Panel Mounting Structures Subjected to Uplift Pressure: Effects of Foundation Defects

Solar
This study investigates the failure behavior of aluminum solar panel mounting structures subjected to uplift pressure, with particular focus on conditions not typically considered in conventional design, specifically, foundation defects.
Sachi Furukawa, Hiroki Mikami, Takehiro Okuji, Koji Takamori   +3 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

FEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Experimental study on mechanical properties and failure behavior analysis of CFRP riveted joints with gaskets and bushings

Xibei Gongye Daxue Xuebao
The application of gaskets, bushings or their combination can significantly improve the joining strength of composite structures, but there is still a lack of systematic researches on their combined or individual applications. To solve this problem, this
YAN Lu, ZHANG Shang′an, CAO Zengqiang, YAN Han, LU Minxi, HUO Lubin   +5 more
doaj   +1 more source

Prospecting the protein design landscape

FEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona, Katharina T. Stonig, Jens Meiler, Clara T. Schoeder, Monica L. Fernández‐Quintero   +4 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

On mixture failure rate ordering [PDF]

Mixtures of increasing failure rate distributions (IFR) can decrease at least in some intervals of time. Usually this property can be observed asymptotically as time tends to infinity.
Maxim S. Finkelstein, Veronica Esaulova
core  

Failure Behavior of Tunnel Inverted Arch Structure in Carbonaceous Slate Stratum: A Case Study

Engineering Reports
This study investigates the failure behavior of the inverted arch structure in carbonaceous slate stratum. The cracks of the inverted arch are observed in this tunnel, and they are caused by the large deformation of the rock mass.
Yiding Zhao, Hua Zhu, Guo Zhou
doaj   +1 more source