Results 171 to 180 of about 4,757,745 (346)

Technology Adoption in Critical Mass Games: Theory and Experimental Evidence [PDF]

We analyze the choices between two technologies A and B that both exhibit network effects. We introduce a critical mass game in which coordination on either one of the standards constitutes a Nash equilibrium outcome while coordination on standard B is ...
Christian Wey, Claudia Keser, Irina Suleymanova   +2 more
core  

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Dynamic Compressive Behavior, Constitutive Modeling, and Complete Failure Criterion of 30 Vol.% B₄C/2024Al Composite. [PDF]

Materials (Basel)
Yan Q, Zhao Z, Luo T, Li F, Zhao J, Chao Z, Liu S, Mei Y, Zhou F.   +8 more
europepmc   +1 more source

Failure criterion of silver nanowire electrodes on a polymer substrate for highly flexible devices. [PDF]

Sci Rep, 2017
Kim D, Kim SH, Kim JH, Lee JC, Ahn JP, Kim SW.   +5 more
europepmc   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Crankshaft high cycle bending fatigue test method based on the combined extended Kalman filtering algorithm and different failure criterion parameters. [PDF]

PLoS One
Wei Z, Ruidong Y, Sun S, Xiaolin G, Zhentao L.   +4 more
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Unified Failure Criterion Based on Stress and Stress Gradient Conditions. [PDF]

Materials (Basel)
Kwon YW, Markoff EK, DeFisher S.
europepmc   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

A failure criterion for genuinely orthotropic materials and integration of a series of criteria for materials of different degrees of anisotropy. [PDF]

R Soc Open Sci
Xu M, Sitnikova E, Li S.
europepmc   +1 more source