Results 51 to 60 of about 1,725,728 (269)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Development of Scientific and Methodical Providing for the Assessment of Technical Condition of the Automated Systems of Protection of Stationary Objects on the basis of Statistics of Their Operation

open access: yesБезопасность информационных технологий, 2013
In the article methodical provisions on formation of the basic data providing a full and objective assessment of technical condition of existing ASO, being in operation outside a guaranteed life are considered.
Alexander Emelyanovich Grodetsky   +1 more
doaj  

Ще раз про надійність мікропроцесорних пристроїв релейного захисту

open access: yesElektrotehnìka ta Elektroenergetika, 2011
Стаття є продовженням циклу публікацій автора, присвячених надійності мікропроцесорних пристроїв релейного захисту. Наведені у статті статистичні дані, отримані автором, збігаються з даними інших авторів і підтверджують більш високу надійність ...
V. I. Gurevich
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Evaluation of Atmospheric Neutron Failure Rates and Damage Mechanisms of Ultra-high Voltage Thyristor for DC Transmission

open access: yesYuanzineng kexue jishu
As the core of high-voltage direct-current transmission technology, the DC converter valve and its key power device thyristor face a high risk of failure caused by atmospheric neutron when operating in high-altitude areas. The atmospheric neutron failure
PENG Chao1, ZHOU Yang2, CHEN Zhongyuan2, LEI Zhifeng1, MA Teng1, ZHANG Zhangang1, ZHANG Hong1, HE Yujuan1
doaj   +1 more source

A 12-month clinical study comparing four Glass Ionomer Cements for the cementation of orthodontic molar bands

open access: yesAustralasian Orthodontic Journal, 1989
Four different glass ionomer cements were evaluated in vivo as luting agents for orthodontic mohu bands. A sample of 199 patients with full fixed appliances (Begg Light Wire) were monitored over a period of 12 months during active treatment for loose ...
Fricker John P.
doaj   +1 more source

Survival and Failure Rates of Lithium Disilicate Veneers: A Systematic Review [PDF]

open access: yesInternational Journal of Prosthodontics and Restorative Dentistry
Purpose: The purpose of the present systematic review was to assess the clinical survival and failure rates of lithium disilicate (LDS) veneers in the anterior region.
Vidulasri N   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

METHODOLOGY OF DETERMINING THE PARAMETERS OF TRACTION ELECTRIC MOTOR FAILURES WHEN OPERATING TROLLEYBUSES

open access: yesNauka ta progres transportu, 2018
Purpose. The work is aimed to study the change in parameters of traction electric motors of trolleybuses during operation and improvement of the technical state control system, using modern diagnostic methods. Methodology.
Т. P. Pavlenko   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

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