Results 51 to 60 of about 125,880 (255)
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Education through sport with the principle of fair play in pre-war Łódź – a city of cultural differences [PDF]
The educational aspects of sports were recognized during the development of sports along with its educational values, character formation, including the adherence to the fair play principle, primarily in English schools.
Jolanta Kowalska, Piotr Kędzia
doaj +1 more source
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata +10 more
wiley +1 more source
Las manifestaciones del juego limpio en el ejercicio de la actividad cinegética
From yesteryear, there are a collection of rules which make up the action of hunting with the scope of protecting a scenario where the hunters¿ advantage is not to be superior as making the animal impossible or very difficult to get away from the tights ...
José María Pérez Monguió
doaj +1 more source
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy +10 more
wiley +1 more source
The Open Sore of Football: Aggressive Violent Behavior and Hooliganism
Aggression and violence have been a customary part of life that mankind has had to live with from the beginning of time; it has been accepted by society even though it expresses endless negativity.
Gumusgul Osman, Acet Mehmet
doaj +1 more source
Fair Play in a Context of Physical Education and Sports Behaviours. [PDF]
Ludwiczak M, Bronikowska M.
europepmc +1 more source
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source

