Results 141 to 150 of about 2,294,345 (331)

Local Data Debiasing for Fairness Based on Generative Adversarial Training [PDF]

, 2021
Ulrich Aïvodji, François Bidet, Sébastien Gambs, Rosin Claude Ngueveu, Alain Tapp   +4 more
openalex   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Energy-efficient data transmission with proportional rate fairness for NANs of smart grid communication network [PDF]

, 2023
Xiaocheng Wang, Qiaoni Han, Yuan Yin, Haogang Ma   +3 more
openalex   +1 more source

Fair Inference On Outcomes

, 2018
In this paper, we consider the problem of fair statistical inference involving outcome variables. Examples include classification and regression problems, and estimating treatment effects in randomized trials or observational data.
Nabi, Razieh, Shpitser, Ilya
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A Data-Driven Approach to Monitor and Improve Open and FAIR Research Data in a Federated Research Ecosystem

Data Science Journal
In this contribution we present a data-driven approach to monitoring and assessing the state of open and FAIR data in an interdisciplinary, federated research ecosystem.
Markus Kubin, Mojeeb Rahman Sedeqi, Alexander Schmidt, Astrid Gilein, Tempest Glodowski, Vivien Serve, Gerrit Günther, Nina Leonie Weisweiler, Gabriel Preuß, Oonagh Mannix   +9 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The Nansen Legacy Template Generator for Darwin Core and CF-NetCDF

Data Science Journal
The scientific community is growing increasingly aware of the importance of the FAIR data management principles for publishing scientific data. For data providers, this includes creating machine-understandable file structures such as CF-NetCDF files and ...
Luke Marsden, Olaf Schneider
doaj   +1 more source

From Raw Data to FAIR Data: The FAIRification Workflow for Health Research [PDF]

, 2020
Ali Anıl Sınacı, Francisco J. Núñez-Benjumea, Mert Gençtürk, Malte-Levin Jauer, Thomas M. Deserno, Catherine Chronaki, Giorgio Cangioli, Carlos Cavero-Barca, Juan M. Rodríguez-Pérez, Manuel M. Pérez‐Pérez, Gökçe Banu Laleci Ertürkmen, Tony Hernández-Pérez, Eva Méndez, Carlos Luís Parra-Calderón   +13 more
openalex   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source