Results 141 to 150 of about 444,200 (304)

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

open access: yesFEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Harmonizing GCW Cryosphere Vocabularies with ENVO and SWEET. Towards a General Model for Semantic Harmonization

open access: yesData Science Journal
This paper presents the specific process used by members of the Earth Science Information Partners (ESIP) Semantic Harmonization Cluster, to harmonize cryospheric terms gathered by the Global Cryosphere Watch (GCW) with two leading semantic resources ...
Ruth Duerr   +6 more
doaj   +1 more source

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

open access: yesFEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson   +6 more
wiley   +1 more source

Replication data and code for: The role of FAIR principles in high-quality research data documentation: looking at national election studies [PDF]

open access: yes
The FAIR principles as a framework for evaluating and improving open science and research data management have gained much attention over the last years.
Zenk-M\uf6ltgen, Wolfgang, GESIS - Leibniz Institute for the Social Sciences
core   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

D1.4 - FAIR-IMPACT Sustainability Plan: Expanding FAIR solutions across EOSC - D1.4 [PDF]

open access: yes
FAIR-IMPACT: Expanding FAIR solutions across EOSC ran from June 2022 to May 2025 and included 28 partners from 11 countries. The project sought to build on the successful practices, policies, tools, and technical specifications arising from FAIRsFAIR ...
Dillo, Ingrid   +10 more
core   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

A FAIR Data Ecosystem for Science of Science. [PDF]

open access: yesProc Assoc Inf Sci Technol, 2023
Qin J   +4 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

A Data-Driven Approach to Monitor and Improve Open and FAIR Research Data in a Federated Research Ecosystem

open access: yesData Science Journal
In this contribution we present a data-driven approach to monitoring and assessing the state of open and FAIR data in an interdisciplinary, federated research ecosystem.
Markus Kubin   +9 more
doaj   +1 more source

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