Results 121 to 130 of about 24,500,580 (267)

A FAIR Data Ecosystem for Science of Science. [PDF]

open access: yesProc Assoc Inf Sci Technol, 2023
Qin J   +4 more
europepmc   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

OTHER TITLES: The Kansas State Fair, Party on the Prairie, September 11-20, 1998, Hutchinson. 1998 Exhibitor Handbook Premium List: The Kansas State Fair, September 11-20, Hutchinson. 1998 Premium Book.

open access: yes, 1998
Issued in four volumes: Agriculture-Domestic Arts Horses (MISSING PAGES) Livestock Youth "Party on the Prairie!"Program of State Fair events. Also contains rules, regulations, classes of events, prizes, and other pertinent information regarding the ...
Kansas State Fair.
core  

A Data-Driven Approach to Monitor and Improve Open and FAIR Research Data in a Federated Research Ecosystem

open access: yesData Science Journal
In this contribution we present a data-driven approach to monitoring and assessing the state of open and FAIR data in an interdisciplinary, federated research ecosystem.
Markus Kubin   +9 more
doaj   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Catalogue ... annual Burnet County Fair

open access: yes, 1934
A catalog for the Burnett County fair, primarily containing ...
Burnet County Fair (Bertram, Tex.)
core  

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

OTHER TITLE: Kansas State Fair 1958 Premium List.

open access: yes, 1958
THE ONLY FAIR IN KANSAS OWNED AND OPERATED BY THE STATE Under the auspices of The Board of State Fair Managers. Authorized by legislative enactment in 1913 and operated for the benefit of the entire State.
Kansas State Fair.
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

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