Results 101 to 110 of about 24,500,580 (267)

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

Other Titles: Biennial Report of the Kansas State Fair and the Board of State Fair Managers, 1962-1980 Kansas State Fair (1962-1964, 1968-1976) Board of State Fair Managers (1978-1980)

open access: yes, 1962
These biennial reports are summaries of the activities of this agency. They were extracted from a series of Kansas agency reports covering over 100 state agencies and institutions bound together for each biennium., 1959/1960 - 1979/1980.
Kansas. Board of State Fair Managers.
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MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

OTHER TITLES: Premium Book: The Kansas State Fair, September 11-20, 1992, Hutchinson. Shades of Fun. Kansas State Fair 1992 Premium Book. 1992 Premium Book.

open access: yes, 1992
Issued in four volumes: Agriculture-Domestic Arts Horses Livestock Youth.Program of State Fair events. Also contains rules, regulations, classes of events, prizes, and other pertinent information regarding the Kansas State Fair, held once a year in ...
Kansas State Fair.
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PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

OTHER TITLES: Premium Book 84: the Kansas State Fair 1984 Premium Book, Hutchinson, Sept. 11-19. Kansas State Fair 1984 Premium Book. 1984 Premium Book.

open access: yes, 1984
Issued in four volumes: 4-H Agriculture-Youth-Domestic Arts Horses Livestock.Program of State Fair events. Also contains rules, regulations, classes of events, prizes, and other pertinent information regarding the Kansas State Fair, held once a year in ...
Kansas State Fair.
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Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

OTHER TITLES: Kansas State Fair, '91, September 6-15, Hutchinson, Premium Book. The Great Kansas Fun For All! Kansas State Fair 1991 Premium Book. 1991 Premium Book.

open access: yes, 1991
Issued in four volumes: Agriculture-Domestic Arts Horses Livestock YouthProgram of State Fair events. Also contains rules, regulations, classes of events, prizes, and other pertinent information regarding the Kansas State Fair, held once a year in ...
Kansas State Fair.
core  

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

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