Results 91 to 100 of about 2,294,345 (331)
, 2018 Esitys on pidetty Informaatiotutkimuksen yhdistyksen kevätseminaarissa "Avoin julkaiseminen osana avointa tiedettä" 22.5.2018.
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, 2021 Presentation about FAIR Data Management as part of the lecture 'Biomedical Data Management' at the University of Tübingen. The goal is to give the students a quick overview about the FAIR principles and an idea of possible implementations of these principles.
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Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Open Context in a Changing Context: Data Publishing, Interoperability and Governance
Internet ArchaeologyThis paper describes the rationale and strategies behind Open Context, an online data publishing service for archaeology. Launched in 2006, Open Context has published nearly 2.4 million records from 200 projects and sub-projects, representing the work of
Eric Kansa, Sarah Whitcher Kansa
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, 2023 This update is about the work we did in an interdisciplinary team, including epidemiologists, mathematical modellers, data scientists and data engineers, data policy experts, and software engineers to build an open-source FAIR data pipeline (https://www.fairdatapipeline.org,https://github.com/FAIRDataPipeline/).
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Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
The Linguistic Asymmetry Index (LAI): Benchmarking Equity in Multilingual Research Infrastructures
Journal of Open Humanities DataDigital research infrastructures frequently describe themselves as multilingual, yet the degree to which languages are represented, documented, and made accessible depends on metadata policies and aggregation practices that may introduce unevenness. This
Elena Battaner, Paul Spence
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AI Gender Bias, Disparities, and Fairness: Does Training Data Matter? [PDF]
, 2023 Ehsan Latif, Xiaoming Zhaı, Lei Liu
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Corruption and Inequality as Correlates of Social Trust: Fairness Matters More Than Similarity [PDF]
, 2005 Argued is that the fairness of a society affects its level of social trust more than does its homogeneity. Societies with fair procedural rules (democracy), fair administration of rules (freedom from corruption), and fair (relatively equal and unskewed ...
Jong-Sung You
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source