Results 161 to 170 of about 2,278,950 (331)

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

Fair end‐to‐end window‐based congestion control in time‐varying data communication networks [PDF]

, 2019
Suchi Kumari, Anurag Singh
openalex   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Impact of a senior research thesis on students' perceptions of scientific inquiry in distinct student populations

FEBS Open Bio, EarlyView.
This study addressed how a senior research thesis is perceived by undergraduate students. It assessed students' perception of research skills, epistemological beliefs, and career goals in Biochemistry (science) and BDC (science‐business) students. Completing a thesis improved confidence in research skills, resilience, scientific identity, closed gender‐
Celeste Suart, Haley L. Zubyk, Michelle Ogrodnik, Caitlin E. Mullarkey, Felicia Vulcu   +4 more
wiley   +1 more source

A dataset for assessing phytolith data for implementation of the FAIR data principles. [PDF]

Sci Data, 2023
Kerfant C, Ruiz-Pérez J, García-Granero JJ, Lancelotti C, Madella M, Karoune E.   +5 more
europepmc   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

The Role of Open Science in Our Research

BioResources
This editorial considers Open Science, what it is, what are its potential benefits, what are the pillars of engagement upon which it rests, and what are some of the main challenges facing its further adoption by research communities.
Angeles Blanco
doaj  

Addressing barriers in FAIR data practices for biomedical data. [PDF]

Sci Data, 2023
Hughes LD, Tsueng G, DiGiovanna J, Horvath TD, Rasmussen LV, Savidge TC, Stoeger T, Turkarslan S, Wu Q, Wu C, Su AI, Pache L, NIAID Systems Biology Data Dissemination Working Group.   +12 more
europepmc   +1 more source

PANGEO multidisciplinary test case for Earth and Environment Big data analysis in FAIR-EASE Infra-EOSC project

, 2023
Marine Vernet, Erwan Bodéré, Jérôme Detoc, Christelle Pierkot, Alessandro Rizzo, Thierry Carval, Thierry Carval   +6 more
openalex   +1 more source

Are Institutional Research Data Policies in the US Supporting the FAIR Principles? A Content Analysis [PDF]

, 2023
Clara Llebot, Diana J. Castillo
openalex   +1 more source