Results 51 to 60 of about 24,500,580 (267)

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

oblassers/fair-data-science: FAIR Data Science Experiment

open access: yes, 2017
<p>First release of the FAIR Data Science proof of concept experiment.</p ...
oblassers
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Advancing FAIR Agricultural Data: The AgReFed FAIR Assessment Tool

open access: yesData Science Journal
The FAIR principles provide guidance for improving the findability, accessibility, interoperability and reuse of research data and other digital objects.
Christiane Bahlo
doaj   +1 more source

A Data Quality Strategy to Enable FAIR, Programmatic Access across Large, Diverse Data Collections for High Performance Data Analysis

open access: yesInformatics, 2017
To ensure seamless, programmatic access to data for High Performance Computing (HPC) and analysis across multiple research domains, it is vital to have a methodology for standardization of both data and services.
Ben Evans   +5 more
doaj   +1 more source

Earth Science and Biodiversity Journals can Improve Support for Data Sharing

open access: yesData Science Journal, 2020
This study reviews research data policies and author instructions of 31 journals from the Earth sciences and from Biodiversity that are published by German learned societies or research institutions. 12 journals don’t address data sharing at all.
Andreas Hübner
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

ARDC FAIR Data 101 self-guided

open access: yes, 2021
FAIR Data 101 v3.0 is a self-guided course covering the FAIR Data principles The FAIR Data 101 virtual course was designed and delivered by the ARDC Skilled Workforce Program twice in 2020 and has now been reworked as a self-guided course.
Brady, Catherine   +13 more
core   +1 more source

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