Results 61 to 70 of about 24,500,580 (267)

Open Practices in Phytolith Research: A Community Survey

Open Quaternary
The open research movement has gained momentum in the last decade and no academic can ignore the necessity to make research more open, as it improves reliability, sustainability and reusability of data.
Javier Ruiz-Pérez, Emma Karoune, Céline Kerfant, Juan José García-Granero, Marco Madella, Carla Lancelotti   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Research Data Governance. The Need for a System of Cross-organisational Responsibility for the Researcher’s Data Domain

Data Science Journal
The integration of research data management into academic workflows presents significant challenges for researchers, resulting in fragmented responsibility and accountability.
Carolin Odebrecht
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

Fair beyond data

, 2020
FAIR was never intended to be just for research data. Increasingly, the FAIR principles are being applied to diverse research outputs and hence a variety of organisations from publishers to institutions are involved in implementing policies and processes
Barbour, Ginny, Cooke, Angus, Simons, Natasha, Borchert, Martin   +3 more
core  

Open Context in a Changing Context: Data Publishing, Interoperability and Governance

Internet Archaeology
This paper describes the rationale and strategies behind Open Context, an online data publishing service for archaeology. Launched in 2006, Open Context has published nearly 2.4 million records from 200 projects and sub-projects, representing the work of
Eric Kansa, Sarah Whitcher Kansa
doaj   +1 more source

Ocean FAIR Data Services

Frontiers in Marine Science, 2019
Well-founded data management systems are of vital importance for ocean observing systems as they ensure that essential data are not only collected but also retained and made accessible for analysis and application by current and future users.
Toste Tanhua, Sylvie Pouliquen, Jessica Hausman, Kevin O’Brien, Pip Bricher, Taco de Bruin, Justin J. H. Buck, Eugene F. Burger, Thierry Carval, Kenneth S. Casey, Steve Diggs, Alessandra Giorgetti, Helen Glaves, Valerie Harscoat, Danie Kinkade, Jose H. Muelbert, Antonio Novellino, Benjamin Pfeil, Peter L. Pulsifer, Anton Van de Putte, Erin Robinson, Dick Schaap, Alexander Smirnov, Neville Smith, Derrick Snowden, Tobias Spears, Shelley Stall, Marten Tacoma, Peter Thijsse, Stein Tronstad, Thomas Vandenberghe, Micah Wengren, Lesley Wyborn, Zhiming Zhao   +33 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Implementing fair lending practices: Advanced data analytics approaches and regulatory compliance

Implementing fair lending practices is crucial for financial institutions to ensure equal access to credit and comply with regulatory requirements. Advanced data analytics approaches offer powerful tools for detecting and mitigating potential biases in ...
Oluwaseun Adeola Bakare, Njideka Ihuoma Okeke, Godwin Ozoemenam Achumie   +2 more
core   +1 more source