Results 61 to 70 of about 27,284,541 (286)

Legal Interoperability and the FAIR Data Principles

, 2021
Data accessible through the EOSC will be governed by the FAIR Principles, embracing Open Science practices. Legal constraints such as ensuring a secure environment where privacy and personal data are protected and where users of the EOSC can be reassured about issues concerning data security, data sovereignty, intellectual property rights, liability ...
Graber-Soudry, Ohad, Minssen, Timo, Nilsson, Daniel, Corrales, Marcelo, Wested, Jakob, Illien, Bénédicte   +5 more
openaire   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

Molecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani, Laura Mariën, Caro De Weerdt, Sanne Wouters, Laure‐Anne Teuwen, Hans Prenen, Katleen Janssens, Timon Vandamme   +7 more
wiley   +1 more source

The impact of leukocyte‐associated RNA retention on platelet RNA‐based cancer detection

Molecular Oncology, EarlyView.
Platelets carry RNA signals that may help detect cancer, but platelet samples can also retain RNA from white blood cells. We found that this retained white blood cell signal did not significantly affect machine learning cancer classification, suggesting that the cancer‐related RNA signal in platelets is largely independent of leukocyte‐associated RNA ...
Michał Sieczczyński, Krzysztof Pastuszak, Anna Samelak‐Czajka, Zuzanna Cemka, Paulina Jackowiak, Tomasz Stefaniak, Sylwia Łapińska‐Szumczyk, Jacek Jassem, Anna J. Żaczek, Matthew T. Rondina, Myron G. Best, Sjors G. J. G. In 't Veld, Anna Supernat   +12 more
wiley   +1 more source

Putting FAIR into practice for ecologists: How to make ecological data more reusable

Ecological Informatics
Ecological data is highly diverse due to the complex nature of the systems they describe. Proper documentation and management are often lacking or not designed for data reuse by others, making the data difficult to find, understand, and at risk to be ...
Cherine C. Jantzen, Stefan J.G. Vriend
doaj   +1 more source

FAIR for AI: An interdisciplinary and international community building perspective

Scientific Data, 2023
A foundational set of findable, accessible, interoperable, and reusable (FAIR) principles were proposed in 2016 as prerequisites for proper data management and stewardship, with the goal of enabling the reusability of scholarly data.
E. A. Huerta, Ben Blaiszik, L. Catherine Brinson, Kristofer E. Bouchard, Daniel Diaz, Caterina Doglioni, Javier M. Duarte, Murali Emani, Ian Foster, Geoffrey Fox, Philip Harris, Lukas Heinrich, Shantenu Jha, Daniel S. Katz, Volodymyr Kindratenko, Christine R. Kirkpatrick, Kati Lassila-Perini, Ravi K. Madduri, Mark S. Neubauer, Fotis E. Psomopoulos, Avik Roy, Oliver Rübel, Zhizhen Zhao, Ruike Zhu   +23 more
doaj   +1 more source

Overcoming platinum resistance by the disulfiram metabolite CuET in novel preclinical models of human carcinomas

Molecular Oncology, EarlyView.
Cisplatin‐resistant cancer cells survive DNA‐damaging platinum‐based treatment yet remain sensitive to CuET‐induced proteotoxic stress. The distinct mechanism of action allows CuET to overcome and eliminate cisplatin‐resistant tumour cells, unless highly expressed metallothioneins (MTs) interfere with CuET, thereby highlighting MT levels as candidate ...
Stefanos Arampatzis, Tereza Buchtová, Jirina Bartkova, Marie Lund Bay, Christoffer Lynge Halvorsen, Zuzana Machacova, Zdenek Skrott, Martin Mistrik, Ekaterina Dulina, Miguel Andujar‐Sanchez, Estrid Høgdall, Tine Henrichsen Schnack, Claus Høgdall, Berit Jul Mosgaard, Marie Boennelycke, Jacob Brink Laursen, Allan Jensen, Susanne K. Kjær, Tuula Kallunki, Robert Strauss, Jiri Bartek   +20 more
wiley   +1 more source

How are we FAIR-ing? Creating a FAIR self-assessment checklist for data repositories

IASSIST Quarterly
In 2023, a team from a local grant-funded medical data repository requested guidance from Penn Libraries on evaluating the extent to which their repository was FAIR-enabling.
Lauren Phegley, Lynda Kellam
doaj   +1 more source

Understanding FAIR Data Principles for Open Science

, 2021
The presentation titled "Understanding FAIR Data Principles for Open Science" was delivered in the Refresher Course in Changing Role of Use of ICT, Open Distance Learning, Open Source Resources and Online Support System in Higher Education and Research ...
Das, Anup Kumar
core   +1 more source

Versatile vector tools for efficient protein screening across multiple expression systems

FEBS Open Bio, EarlyView.
A unified vector toolkit enables rapid protein expression screening across E. coli, insect, and mammalian cells. A single primer pair amplifies the target gene, which is inserted into any vector via a standardized interface. This streamlined workflow eliminates repeated cloning steps, accelerating the identification of optimal expression conditions for
Zhimin Zhu, Yaqing Liu, Lei Qin, Feng Yu, Qisheng Wang, Yahui Liu   +5 more
wiley   +1 more source

Open Data Challenges in Climate Science

Data Science Journal, 2020
The purpose of this paper is to explore challenges in open climate data experienced by data scientists at the Centre for Environmental Data Analysis (CEDA). This paper explores two of the five V’s of Big Data, Volume and Variety.
Francesca Eggleton, Kate Winfield
doaj   +1 more source