Results 61 to 70 of about 1,676,158 (297)

Lex sportiva and fair-play

open access: yesZbornik Radova Pravnog Fakulteta u Splitu, 2011
Basically the work consists of the denial of a claim, which is largely entrenched in doctrine, according to which lex sportiva represents a transnational or non-national legal system, on the one hand, and affirmation of fair-play, as the principle that ...
Miodrag Mićović
doaj  

Conflicting Views on Fair Siting Processes: Evidence from Austria and the U.S. [PDF]

open access: yes, 1996
The authors maintain that, by granting legitimacy to different notions of fairness and building on common values such as responsibility, it is possible to design siting procedures that promote social cohesion, trust and a sense of fair ...
Fitzgerald, Kevin B.   +1 more
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

British fair play: sport across diasporas at the BBC World Service [PDF]

open access: yes, 2011
This chapter uses archive material to explore the role of sports broadcasting on the BBC World Service in the twentieth century.Whereas the service's early audiences were expatriate British listeners, the BBC WS recruited different diasporic audiences ...
Goldblatt, David   +2 more
core  

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Education through sport with the principle of fair play in pre-war Łódź – a city of cultural differences [PDF]

open access: yesStudia z Teorii Wychowania
The educational aspects of sports were recognized during the development of sports along with its educational values, character formation, including the adherence to the fair play principle, primarily in English schools.
Jolanta Kowalska, Piotr Kędzia
doaj   +1 more source

'Plough Bullocks' and Related Plough Monday Customs in the Nottingham Area, 1800-1930 [PDF]

open access: yes, 2005
This paper describes Plough Monday activities in the city of Nottingham, which died out in the inter-war years, and chronicles the establishment of its Plough Day Fair in 1712.
Millington, Peter
core  

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