Results 71 to 80 of about 125,880 (253)

Social-regulavive concept «fair play» in english linguaculture

open access: yesRussian journal of linguistics: Vestnik RUDN, 2009
Linguacultural social-regulative concept «fair play» is analized in the article. The concept contains moral-ethic values (the highest orientations) and norms of behaviour.
L A Gunina
doaj  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

open access: yesFEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca   +6 more
wiley   +1 more source

Identification and evaluation of fair play behaviors in juvenile football Cadiz

open access: yesE-balonmano.com: Revista de Ciencias del Deporte, 2014
Objective: To analyse sportsmanlike and unsportsmanlike conduct of football players in juvenile category (aged from 10-12), as well as sanctioning of players and their trainers.
Javier Lamoneda Prieto   +3 more
doaj   +2 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

open access: yesFEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa   +2 more
wiley   +1 more source

ROLE OF SPORT ACTIVITIES IN THE FORMATION OF ETICHO-MORAL VALUES

open access: yesSport şi Societate, 2012
Moral values play an essential role in the orientation of UMA, us, in setting the objectives and goals to be attained, the strategies and ways of action; they, the matter shall be referred to states or modes of action, siderate cone to be delisted ...
Popescu V.
doaj  

Fair Play Kapsamında Sporcularda Saygı Kavramı: Mecburiyet/ Ahlaki Yükümlülük

open access: yesSportif Bakış Spor ve Eğitim Bilimleri Dergisi, 2023
Bu çalışma sporcuların saygı kavramını nasıl değerlendirdiklerinin belirlenmesi amacıyla hazırlanmıştır. Çalışma kapsamında saygı kavramının müsabaka sonucuna etkileri, galibiyet ve mağlubiyet durumunda saygı gösterimi, sporcuların hakem kararlarına ...
İlyas GÖRGÜT
doaj  

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

open access: yesFEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen   +9 more
wiley   +1 more source

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