Results 101 to 110 of about 965,165 (311)
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The Legacy of Cambodia’s Hybrid Court: Promoting Fair Trial Rights?
Jurnal HAMThe mandate of the Extraordinary Chambers in the Courts of Cambodia (ECCC) concluded in 2022, marking the end of its nearly two-decade presence in Cambodia.
Somaly Kum
doaj +1 more source
Human trafficking, victims’ rights and fair trials [PDF]
, 2018 Cases of human trafficking are known to be difficult to prosecute. In this article we identify several issues in the law of evidence that may contribute to these difficulties.
Fouladvand, Shahrzad, Ward, Tony
core +3 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
THE RIGHT TO A FAIR TRIAL IN THE DYNAMIC INTERPRETATION OF THE EUROPEAN COURT OF HUMAN RIGHTS [PDF]
Challenges of the Knowledge Society, 2016 The European Court of Human Rights has constantly highlighted the importance of Article 6 of the Convention and by a dynamic interpretation, the jurisprudence of the Strasbourg Court has gradually enriched the content and the practical impact of the ...
Alexandra PANAIT
doaj
The Right to Cross-Examination and Witness Protection in Ethiopia: Comparative Overview
Mizan Law Review, 2018 Cross-examination particularly in the context of criminal trial is a human right recognized in international human rights law and the Ethiopian constitution.
Tadesse Melaku
doaj +1 more source
Innocence, Harmless Error, and Federal Wrongful Conviction Law [PDF]
, 2005 This Article examines the body of law emerging in cases brought by former criminal defendants once exonerated, often through DNA testing, which may fundamentally reshape our criminal justice system.
Garrett, Brandon L.
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Utrecht Law Review, 2011 Since the adoption of the UN Convention of the Rights of the Child in 1989, the right to participation has been recognised internationally as one of the general principles of children's legal status.
Annemarieke Beijer, Ton Liefaard
doaj +1 more source
The Anonymous Accused: Protecting Defendants\u27 Rights in High-Profile Criminal Cases [PDF]
, 2003 The public\u27s interest in high-profile crimes and the media\u27s coverage of high-profile trials have significantly increased over the past. fifty years, raising significant concerns about a high-profile defendant\u27s right to a fair trial.
Morris, Jaime N
core