Results 61 to 70 of about 103,702 (261)
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
One of important principle every democratic state is rule of law. The rule of law in countries of democratic tradition, so-called countries of western democracy, is not questioned any more.
Nihad Ukić
doaj
Hak Konstitusional Korban atas Pengadilan HAM yang Kompeten, Independen, dan Imparsial
Court of Human Rights, guarantee a fair trial for the sake of protecting human and human dignity must be realized in line with the principles of the Indonesian nation berketuhanan and equitable.
Yustina Trihoni Nalesti Dewi
doaj +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Trial within a reasonable time in comparative law [PDF]
The right to a trial within a reasonable time as part of the right to a fair trial is one of the fundamental human rights that belongs to all people without distinction.
Bećirović-Alić Maida M.
doaj
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Nonostante le varie controversie che circondano il concetto di “giustizia”, quando si parla di una “decisione giusta”, il concetto può essere ridotto a schemi razionali e abbastanza controllabili sul suo significato.
Michele Taruffo
doaj
Gains from no real PAINS: Where 'Fair Trial Strategy' stands in the development of multi-target ligands. [PDF]
Sun J, Zhong H, Wang K, Li N, Chen L.
europepmc +1 more source

