Results 61 to 70 of about 103,702 (261)

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

open access: yesFEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

THE CONCEPT „INDEPENDENT AND IMPRATIAL TRIBUNAL” IN THE PRACTICE OF THE EUROPEAN COURT OF HUMAN RIGHTS

open access: yesPravo, 2012
One of important principle every democratic state is rule of law. The rule of law in countries of democratic tradition, so-called countries of western democracy, is not questioned any more.
Nihad Ukić
doaj  

Hak Konstitusional Korban atas Pengadilan HAM yang Kompeten, Independen, dan Imparsial

open access: yesJurnal Konstitusi, 2016
Court of Human Rights, guarantee a fair trial for the sake of protecting human and human dignity must be realized in line with the principles of the Indonesian nation berketuhanan and equitable.
Yustina Trihoni Nalesti Dewi
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Trial within a reasonable time in comparative law [PDF]

open access: yesStrani pravni život, 2019
The right to a trial within a reasonable time as part of the right to a fair trial is one of the fundamental human rights that belongs to all people without distinction.
Bećirović-Alić Maida M.
doaj  

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

La decisione giusta

open access: yesRevista Ítalo-Española de Derecho Procesal, 2019
Nonostante le varie controversie che circondano il concetto di “giustizia”, quando si parla di una “decisione giusta”, il concetto può essere ridotto a schemi razionali e abbastanza controllabili sul suo significato.
Michele Taruffo
doaj  

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