Results 161 to 170 of about 5,302 (301)

Ensuring FAIRness in Machine Learning Projects

Subsymbolic approaches like machine learning (ML), deep learning, and Large Language Models (LLMs) have significantly advanced Artificial Intelligence, excelling in tasks such as question answering and ontology matching.
Schimmler, Sonja, Efeoğlu, Şefika, Chen, Zongxiong   +2 more
core  

TME/NIR Dual‐Responsive Zinc‐Based Targeted Nanoagonist for Multimodal Amplification of STING‐Mediated Cancer Immunotherapy

Advanced Science, EarlyView.
A multifunctional nanoagonist (cDZ@IP) enables nano‐metabolite–driven multimodal activation of the STING pathway and enhanced immune recognition, achieving potent antitumor immunity and suppressing tumor growth and metastasis. This strategy highlights the rational design of therapeutic metabolites and establishes a new paradigm bridging nanomedicine ...
Kepeng Hu, Jiawei Wang, Wei Zhang, Zhixuan Wu, Jing Chen, Yujing He, Xiyue Duan, Yaoting He, Xin Xin, Haoyi Xiang, Yijing Wang, Chengwei Wu, Yang Yi, Qing Meng, Yuqian Qiao, Kui Cheng, Xiaojun Long, Zhangfa Song   +17 more
wiley   +1 more source

Cross‐Modal Denoising and Integration of Spatial Multi‐Omics Data with CANDIES

Advanced Science, EarlyView.
In this paper, we introduce CANDIES, which leverages a conditional diffusion model and contrastive learning to effectively denoise and integrate spatial multi‐omics data. We conduct extensive evaluations on diverse synthetic and real datasets, CANDIES shows superior performance on various downstream tasks, including denoising, spatial domain ...
Ye Liu, Wanpeng Zou, Yuekai Li, Jiayi Wang, Mingxuan Cai, Hongmin Cai   +5 more
wiley   +1 more source

Exploration of the regulatory system in the construction of an integrated data market

大数据
The construction of a regulatory system is an important part of building the national integrated data market. The lawful and compliant operation of the data market, as well as the assurance of fairness, openness, and impartiality, all depend on the ...
Ye Yazhen, Zhu Yangyong
doaj  

Ethics and bias in emotional AI. [PDF]

Front Artif Intell
S SG, Chandrasekaran B, J O.
europepmc   +1 more source

High‐Throughput Screening and Interpretable Machine Learning for Rational Design of Bimetallic Catalysts for Methane Activation

Advanced Science, EarlyView.
ABSTRACT Methane's efficient catalytic removal is vital for sustainable development. Bimetallic catalysts, though promising for methane activation, pose a design challenge due to their complex compositional space. This work introduces an integrated framework that combines high‐throughput density functional theory (DFT) and interpretable machine ...
Mingzhang Pan, Tian Zhang, Jiawei Dong, Yubao Xie, Kaifeng Zhong, Wei Guan, Haiqiao Wei, Changcheng Fu, Yaqiong Su   +8 more
wiley   +1 more source

Exploring the Dynamics of Perceived Organizational Support, Psychological Safety, and Organizational Justice in Enhancing Nurses' Meaningful Work: A Moderated Mediation Model. [PDF]

Nurs Res Pract
Ibrahim IA.
europepmc   +1 more source

Kinsenoside Targets IDH1 to Restore Microglial Immune‐Metabolic Homeostasis for Alzheimer's Disease Therapy

Advanced Science, EarlyView.
Dysregulated TCA cycle contributes to Alzheimer's disease (AD) pathogenesis. Here, we show that microglial isocitrate dehydrogenase 1 (IDH1) is a critical driver. Elevated IDH1 disrupts citrate metabolism and mitochondrial function, exacerbating AD pathology.
Qianqian Li, Yajin Liao, Yan‐bo Zhao, Hongxing Wu, Tong Jin, Shuoshuo Li, Yuhan Liu, Peng Li, Songying Ouyang, Zekai Li, YuTing Xia, Qian Hua, Rui‐Yuan Pan, Zengqiang Yuan   +13 more
wiley   +1 more source

Five ways to get a grip on using the Corruption Perceptions Index to support internationally trained physicians. [PDF]

Health Aff Sch
Ashworth N, Kain N, Hamayeli-Mehrabani P, Hernandez-Ceron N, Hurava I, Kumar K.   +5 more
europepmc   +1 more source

FAIRness, openness and its impact

A short presentation at an Open Research Workshop at Nottingham Trent University. 
openaire   +2 more sources