Results 91 to 100 of about 7,761,607 (342)

Research of Fall Detection and Fall Prevention Technologies: A Systematic Review

IEEE Access, 2019
Falls are abnormal activity events that occur infrequently; however, they are serious health problems among elderly individuals. With the advancements of technologies, falls have been widely studied by scientific researchers to minimize serious ...
Lingmei Ren, Yanjun Peng
semanticscholar   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Effect of a Home-Based Exercise Program on Subsequent Falls Among Community-Dwelling High-Risk Older Adults After a Fall: A Randomized Clinical Trial.

Journal of the American Medical Association (JAMA), 2019
Importance Whether exercise reduces subsequent falls in high-risk older adults who have already experienced a fall is unknown. Objective To assess the effect of a home-based exercise program as a fall prevention strategy in older adults who were ...
T. Liu-Ambrose, Jennifer C. Davis, J. Best, L. Dian, K. Madden, W. Cook, C. Hsu, K. Khan   +7 more
semanticscholar   +1 more source

Matrix metalloproteinase‐9 regulates cell adhesion and membrane protrusive activity of ovarian cancer cells

FEBS Open Bio, EarlyView.
Matrix metalloproteinase‐9 (MMP9) drives ovarian cancer progression. Using MMP9‐null cells (M9‐KO) created from ovarian cancer cells, we found MMP9 loss did not block Epidermal Growth Factor (EGF)‐driven E‐cadherin dissolution or EMT but delayed and reduced EGF‐driven membrane protrusions. Transient MMP9 re‐expression drove membrane protrusion.
Claire Strauel, Sam Bennett, Natalie Ehlinger, Nelson Cook, Katelyn Marvin, Caleb L. Lines, Sam Reyes, Brooke Kirby, Shawn M. Ellerbroek   +8 more
wiley   +1 more source

Anthropological-eshatological paradigm of christian apologists. Part I

Волинський благовісник, 2019
One of the major questions that have plagued humanity throughout its history has been the question of what kind of person it is for its purpose. Depending on the answer, outlines of purpose and meaning of life were obtained.
priest Alexander Khoroshko
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Staff Experiences in Managing Incidents in Nursing Homes: A Descriptive Qualitative Study

Journal of Multidisciplinary Healthcare, 2023
Rista Fauziningtyas,1– 3,* Mei Chan Chong,1,* Herley Windo Setiawan,4 Maw Pin Tan5,* 1Department of Nursing Science, Faculty of Medicine, Universiti Malaya, Kuala Lumpur, Malaysia; 2Faculty of Nursing, Universitas Airlangga, Surabaya ...
Fauziningtyas R, Chong MC, Setiawan HW, Tan MP   +3 more
doaj  

The rise and fall of the Cretaceous Hot Greenhouse climate

Global and Planetary Change, 2018
A compilation of foraminiferal stable isotope measurements from southern high latitude (SHL) deep-sea sites provides a novel perspective important for understanding Earth's paleotemperature and paleoceanographic changes across the rise and fall of the ...
B. Huber, K. MacLeod, D. Watkins, M. Coffin   +3 more
semanticscholar   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source