Results 71 to 80 of about 7,761,607 (342)
MedEdPORTAL, 2014 Abstract This workshop is intended to promote and enhance active learning and problem-solving among third-year medical students. At our institution, we decided to transform the existing didactic and case-based falls/fall-prevention workshop into a team-based learning (TBL) format, integrating two minimum geriatric competencies and the latest evidence ...
openaire +2 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Balance control in elderly people with osteoporosis
Journal of the Formosan Medical Association, 2014 Osteoporosis is a prevalent health concern among older adults and is associated with an increased risk of falls that incur fracture, injury, or mortality.
Wei-Li Hsu +3 more
doaj +1 more source
Computing Brain White and Grey Matter Injury Severity in a Traumatic Fall
Mathematical and Computational Applications, 2020 In the real world, the severity of traumatic injuries is measured using the Abbreviated Injury Scale (AIS). However, the AIS scale cannot currently be computed by using the output from finite element human computer models, which currently rely on maximum
Christophe Bastien +3 more
doaj +1 more source
bioRxiv, 2018 Fall armyworm, Spodoptera frugiperda, is a crop pest native to the Americas, which has invaded and spread throughout sub-Saharan Africa within two years. Recent estimates of 20-50% maize yield loss in Africa suggest severe damage to livelihoods.
R. Early +3 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon +6 more
wiley +1 more source
Clinical, Radiographic and Magnetic Resonance Imaging Evaluation of Cervical Spine Trauma [PDF]
International Journal of Anatomy Radiology and Surgery, 2016 Introduction: Cervical spine trauma occurs in 1.5 to 3% of patients with major trauma and in 10% of patients with major trauma and serious head injury. Imaging plays an important role in the diagnosis of spinal injuries.
Aditi Himaunshu Dongre +2 more
doaj +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Effects of alcohol consumption on maxillofacial fractures in simple falls
Clinical and Experimental Dental Research, 2020 Objectives This study aimed to investigate the effects of alcohol consumption (AC) on maxillofacial fractures caused by falls on a level surface (simple falls).
Shunsuke Hino +5 more
doaj +1 more source