Results 171 to 180 of about 67,918 (318)
The Role of Macrophages in Cancer: From Basic Research to Clinical Applications
Monocytes infiltrate the tumor microenvironment (TME) and differentiate into macrophages, which polarize into proinflammatory, antitumor M1 cells or immunosuppressive, protumor M2 cells. Within the TME, M2‐type tumor‐associated macrophages (TAMs) predominate and drive tumor growth, angiogenesis, and metastasis. Therapeutic strategies therefore focus on
Zhimei Liu +5 more
wiley +1 more source
Physiologically‐Based Pharmacokinetic Modeling of the PARP Inhibitor Niraparib
ABSTRACT A physiologically‐based pharmacokinetic (PBPK) model of niraparib and its primary metabolite using a relevant virtual cancer population is reported here. A series of in vitro experiments using liver S9, microsomes, and hepatocytes with various inhibitors and recombinant supersomes demonstrated that niraparib is specifically metabolized by ...
Gareth J. Lewis +3 more
wiley +1 more source
The Imaging of Primary Fallopian Tube Carcinoma: A Literature Review. [PDF]
Iacobellis G +4 more
europepmc +1 more source
Fallopian Tube Transitional Cell Carcinoma [PDF]
National Cancer Institute
openalex +1 more source
ABSTRACT Purpose This study examined whether the incidence of retained products of conception (RPOC) differs between hormone replacement cycles (HRC) and natural ovulation cycles (NC) in frozen–thawed embryo transfer (FET) pregnancies. Methods We retrospectively analyzed 425 clinical pregnancies following FET at a single center from 2017 to 2021 ...
Akiko Shimada +8 more
wiley +1 more source
Laparoscopic management of a mature cystic teratoma in the fallopian tube. [PDF]
Akdemir A, Mutu C, Serin G, Özdemir N.
europepmc +1 more source
Optimizing Maternal Microbiome: Role in Improved Conception and Pregnancy Outcome
Maternal microbiome optimization: Minimized risk and simple corrective steps. ABSTRACT Purpose To evaluate the role of optimizing the maternal microbiome in improving pregnancy outcomes, focusing on preconception and early gestation, and to propose practical diagnostic and preventive strategies, particularly in low‐ and middle‐income countries (LMIC ...
Eytan R. Barnea +7 more
wiley +1 more source
Stable expansion of high-grade serous ovarian cancer organoids requires a low-Wnt environment
Berger, H. +13 more
core +1 more source

