Results 91 to 100 of about 200 (180)

Alterations to longitudinal muscle morphology and mechanical function following immobilization and recovery in female ovariectomized and intact rats

open access: yesExperimental Physiology, EarlyView.
Abstract Serial sarcomere number (SSN) is reduced following immobilization of a muscle in a shortened position in male rodents thereby impairing muscle contractile function. However, in female rodents the effects of oestrogen on SSN and mechanical changes following immobilization and re‐ambulation are unknown.
Alexandra Q. Kirkup   +3 more
wiley   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington   +4 more
wiley   +1 more source

HYDATID TORSION OF THE FALLOPIAN TUBE. DIAGNOSTIC DIFFICULTIES (CLINICAL CASE)

open access: yesМать и дитя в Кузбассе, 2019
In the structure of acute gynecological diseases, the twisting of the uterine appendages is 7.0 %. The disease does not always have a typical clinical and laboratory picture and requires ultrasound examination in dynamics.
Сергей Валерьевич Рыбников   +4 more
doaj  

Tumor Infiltrating Lymphocyte Therapy Combined With PD‐1/LAG‐3 Inhibition in Patients With Recurrent Platinum‐Resistant Ovarian Cancer

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1735-1749, 1 October 2026.
The detection of tumor‐infiltrating lymphocytes (TILs) is a positive prognostic factor in ovarian cancer. Moreover, TILs are significantly boosted by immunotherapy, though ovarian cancer patients have seen limited benefit from immune therapies. This study investigated the safety and feasibility of TIL therapy combined with PD‐1 and LAG‐3 inhibitors in ...
Tine J. Monberg   +9 more
wiley   +1 more source

The 9th Edition of the UICC TNM Classification of Malignant Tumours: Updates and Rationale for Change

open access: yesInternational Journal of Cancer, Volume 159, Issue 7, Page 1588-1601, 1 October 2026.
ABSTRACT The standard for assessing and recording the extent of the tumour, a necessity for most malignancies, is the Tumour Node Metastases (TNM) classification. The Union for International Cancer Control (UICC) TNM committee has defined this since the early 1950s.
James D. Brierley   +8 more
wiley   +1 more source

A COMPLEX OF MEASURES FOR INTRAOPERATIVE PREVENTION OF POSTOPERATIVE ADHERE FORMATION AND REOCCLUSION OF THE UTERINE TUBES DURING ENDOSURGICAL CORRECTION OF DISTAL TUBE OCCLUSION IN WOMEN WITH TUBE-PERITONEAL INFERTILITY

open access: yesМать и дитя в Кузбассе
Female infertility remains one of the important problems of modern gynecology. The most common form of female infertility is tubal-peritoneal, which develops as a result of inflammatory diseases of the uterine appendages or surgical interventions on the ...
Сергей Валериевич Рыбников   +5 more
doaj  

Artificial Intelligence Resources for the Screening of Titles and Abstracts in Systematic Reviews: A Scoping Review

open access: yesCochrane Evidence Synthesis and Methods, Volume 4, Issue 5, September 2026.
ABSTRACT Introduction Artificial intelligence (AI) is a branch of technology enabling machines to emulate complex human skills; it can also entail problem‐solving using bioinspired methods. It is used for automating systematic literature reviews (SLR), that is, defining a clinical question, locating relevant literature, preliminary screening, study ...
Ana M. Barragán   +5 more
wiley   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

open access: yesClinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu   +6 more
wiley   +1 more source

Age, lifestyle, and disease affect ciliary transport in the human fallopian tube

open access: yesScientific Reports
The synchronized beating of ciliated cells within the human fallopian tube is crucial for the transport of the oocyte and the early embryo. To date, the precise effects of age, lifestyle, and disease on ciliary beating in the human fallopian tube are still unknown.
Neville, Caoimhe   +6 more
openaire   +2 more sources

A multiplex tissue resource for high‐resolution spatial protein profiling in the Human Protein Atlas

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Spatially resolved protein expression is essential for understanding tissue organization, cellular specialization, and protein function. The open‐access Human Protein Atlas database (www.proteinatlas.org) has generated an extensive antibody‐based tissue resource for a majority of the human protein‐coding genes using conventional ...
Borbala Katona   +9 more
wiley   +1 more source

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