Results 61 to 70 of about 14,852 (255)

Detecting FR‐⍺ Expression Level in Cytology Effusion Specimens From Ovarian Cancer and Comparing It With Tissue Specimens

Diagnostic Cytopathology, EarlyView.
ABSTRACT Background Folate receptor‐⍺ (FR‐⍺) is an attractive target for targeted therapy. Mirvetuximab soravtansine (MIRV) has been approved by the United States Food and Drug Administration (FDA) for treating adult patients with FR‐⍺ positive, platinum‐resistant epithelial ovarian cancer, fallopian tube cancer, or primary peritoneal cancer. Therefore,
Yadan Ma, Xiaofei Yu, Xiaohong Duan, Siqian Huang, Sishi Bai, Baizhou Li   +5 more
wiley   +1 more source

Is Surgical Intervention for Ectopic Pregnancy in a Low Resource Set-Up Avoidable? [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background - Ectopic pregnancy is one of the most common life threatening complications in the first trimester of pregnancy having significant adverse effects on future pregnancy outcome, particularly if salpingectomy is used as the modality of ...
Anindita Sinha Babu, Jayeeta Roy, Dipanwita Das, Dipankar Banerjee   +3 more
doaj   +1 more source

The cervico‐vaginal DNA methylation WID‐qEC test: An epigenetic marker associated with ovarian cancer in the absence of endometrial and cervical cancer

International Journal of Cancer, EarlyView.
What's New? The DNA methylation‐based WID‐qEC test has been validated for the accurate detection of endometrial and cervical cancers using cervico‐vaginal samples. However, a small proportion of women test positive despite the absence of these cancers. This study explored the associated biological and clinical characteristics to inform potential follow‐
Elisa Redl, Chiara Herzog, Charlotte Vavourakis, James Barrett, Allison Jones, Iona Evans, Daniel Reisel, Ranjit Manchanda, Line Bjørge, Michal Zikan, David Cibula, Twana Alkasalias, Angelique Flöter Rådestad, Kristina Gemzell‐Danielsson, Louis Dubeau, Nicola MacDonald, Davor Jurkovic, Nora Pashayan, Martin Widschwendter   +18 more
wiley   +1 more source

Spontaneous hemoperitoneum in a 29‐week pregnancy with a history of endometriosis: A case report and review of the literature

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 31-37, April 2025.
Abstract Spontaneous hemoperitoneum in pregnancy (SHIP) is defined as sudden, nontraumatic intraperitoneal bleeding that occurs during pregnancy or up to 42 days postpartum. The incidence ranges between 4 and 4.9 per 100 000 births. Although seen rarely, it is associated with perinatal morbidity and mortality due to maternal hemodynamic instability ...
Shamsi Mehdiyev, Fatma Basak Tanoglu, Esma Demir Altuncu, Engin Oral   +3 more
wiley   +1 more source

Rare hydrosalpinx in a sexually inactive adolescent successfully treated with laparoscopy

Gynecology and Minimally Invasive Therapy, 2017
The majority of cases of symptomatic hydrosalpinx needing treatment are caused by sexually transmitted diseases. However, here, we present a rare case of a hydrosalpinx occurring in a sexually-inactive adolescent girl successfully treated with ...
Masumi Takeda, Takashi Miyatake, Asuka Tanaka, Serika Kanao, Ai Miyoshi, Mayuko Mimura, Masaaki Nagamatsu, Takeshi Yokoi   +7 more
doaj   +1 more source

STING pathway expression in low‐grade serous carcinoma of the ovary: an unexpected therapeutic opportunity?

The Journal of Pathology: Clinical Research, 2021
Ovarian carcinoma histotypes are distinct diseases with variable clinical outcomes and response to treatment. There is a need for new subtype‐specific treatment modalities, especially for women with widespread and chemo‐resistant disease.
Jutta Huvila, Dawn R Cochrane, Monica Ta, Christine Chow, Kendall Greening, Samuel Leung, Anthony N Karnezis, Analisa DiFeo, David G Huntsman   +8 more
doaj   +1 more source

Clinical trial of safety and antitumor activity of farletuzumab ecteribulin in patients with platinum‐resistant ovarian cancer: Phase I expansion results

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective In the dose‐escalation part of Study 101, which included multiple tumor types, objective responses were observed in 10 of 22 patients across multiple dose levels of farletuzumab ecteribulin (FZEC). We explored the safety/antitumor activity of FZEC in patients with platinum‐resistant ovarian cancer (PROC) from the Study 101 expansion ...
Kan Yonemori, Mayu Yunokawa, Koji Matsumoto, Kazuhiro Takehara, Kosei Hasegawa, Yasuyuki Hirashima, Hidenori Kato, Hiroki Ikezawa, Yohei Otake, Wataru Yusa, Takuma Miura, Shin Nishio   +11 more
wiley   +1 more source

Diagnostic and Management of Undescended Ovary – A Preoperative Dilemma: A Case-Based Systematic Review

International Journal of Women's Health, 2022
Ioana Anca Stefanopol,1,2,* Liliana Baroiu,3,4 Georgiana Bianca Constantin,1,5 Dumitru Marius Danila,2,6,* Lucreţia Anghel,3,7,* Alexandru Nechifor,3,8,* Alin Laurenţiu Tatu3,8– 10 1Department of Morphological and Functional
Stefanopol IA, Baroiu L, Constantin GB, Danila DM, Anghel L, Nechifor A, Tatu AL   +6 more
doaj  

IDENTIFICATION OF DISPLACED ENDOMETRIAL GLANDS AND EMBRYONIC DUCT REMNANTS IN FEMALE FOETAL REPRODUCTIVE TRACT: POSSIBLE PATHOGENETIC ROLE IN ENDOMETRIOTIC AND PELVIC NEOPLASTIC PROCESSES

Frontiers in Physiology, 2012
Background: Recent findings strongly promoted the hypothesis that common pelvic gynaecological diseases including endometriosis and ovarian neoplasia may develop de novo from ectopic endometrial-like glands and/or embryonic epithelial remnants. To verify
Jean eBouquet De Joliniere, Jean Marc eAyoubi, Guy eLesec, Pierre eValidire, Alexandre eGoguin, Luca eGianaroli, Jean Bernard eDubuisson, Anis eFeki, Jean eGogusev   +8 more
doaj   +1 more source

Organoids and organ‐on‐a‐chip models for investigating the pathophysiology of the human reproductive system

Interdisciplinary Medicine, EarlyView.
Organoids and organ‐on‐a‐chips are advancing reproductive system research. In the female reproductive system, applications include cancer organoid models, placental chips, and hormone simulation models. For the male reproductive system, research focuses on drug resistance mechanisms, co‐culture platforms, and infertility studies. These refined in vitro
Hongqi Zhang, Shiwen Deng, Fangfang Jin, Jiayao Qu, Xiang Fan, Peng Chen, Xinrong Fan   +6 more
wiley   +1 more source