Results 171 to 180 of about 63,938 (281)

Nigericin‐Triggered Phosphodynamics in Inflammasome Formation and Pyroptosis

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Innate immune signaling relies heavily on phosphorylation cascades to mount effective immune responses. Although traditional innate immune signaling cascades following TLR4 stimulation have been investigated through a temporally quantitative phosphoproteomic lens, far fewer studies have applied these methods to distinct signaling following the
Vanya Bhushan   +5 more
wiley   +1 more source

Proteome‐Wide Analysis of Palmitoylated Proteins in Macrophages Reveals Novel Insights Into Early Immune Signaling

open access: yesPROTEOMICS, EarlyView.
ABSTRACT Protein S‐palmitoylation, a reversible lipid modification, plays critical roles in regulating protein function and localization. However, its comprehensive role in the rapid reprogramming of macrophages during early immune responses remains incompletely understood.
Hyojung Kim   +4 more
wiley   +1 more source

Why Autonomous Vehicles Are Not Ready Yet: A Multi‐Disciplinary Review of Problems, Attempted Solutions, and Future Directions

open access: yesJournal of Field Robotics, EarlyView.
ABSTRACT Personal autonomous vehicles can sense their surrounding environment, plan their route, and drive with little or no involvement of human drivers. Despite the latest technological advancements and the hopeful announcements made by leading entrepreneurs, to date no personal vehicle is approved for road circulation in a “fully” or “semi ...
Xingshuai Dong   +13 more
wiley   +1 more source

Generative AI—the Transgression of Technology

open access: yesSystems Research and Behavioral Science, EarlyView.
ABSTRACT This article offers a systems‐theoretical analysis of generative artificial intelligence (GenAI) grounded in Niklas Luhmann's sociology of technology. It addresses a central conceptual problem: How GenAI can be understood within a theoretical framework that has traditionally defined technology as a means of stabilising action through causal ...
Jesper Tække
wiley   +1 more source

Normalizing the Shamed Self: Stigma, Neutralization and “Narrative Credibility” in Interviews on White‐Collar Transgression

open access: yesSymbolic Interaction, EarlyView.
In this article, I analyze my interviews with Mark (pseudonym), a social scientist who committed major academic fraud in over 50 top‐tier journal articles in the first decade of this century. I explain how stigma played a central role in how Mark and I shaped our interaction. I focus on how Mark, a former Professor and Dean with a distinguished career,
Thaddeus Müller
wiley   +1 more source

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