Results 91 to 100 of about 24,681,994 (291)

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

Resilience Enhancement Strategies for Integrated Energy Systems Against False Data Injection Attacks

发电技术
ObjectivesThe openness of the network makes integrated energy systems vulnerable to cyber attacks, focusing on the resilience enhancement of integrated energy systems (IES) against false data injection attacks (FDIA).MethodsA resilience enhancement ...
WU Lizhen, ZHANG Yongpeng, WEI Jianping, CHEN Wei   +3 more
doaj   +1 more source

Power grid resilience against false data injection attacks

, 2016
Smart Grid security has motivated numerous researches from multiple disciplines. Among the recently discovered security challenges, the False Data Injection (FDI) has drawn great attention from power and energy, computer, and communication research ...
Haibo He, Bo Tang, Bo, Tang, Jun Yan, Yufei Tang, He, Haibo, Yan Sun, Yan, Jun, Tang, Yufei, Sun, Yan   +9 more
core   +1 more source

Detecting stealthy false data injection attacks in the smart grid using ensemble-based machine learning

, 2020
Stealthy false data injection attacks target state estimation in energy management systems in smart power grids to adversely affect operations of the power transmission systems.
Ashrafuzzaman, Mohammad, Chakhchoukh, Yacine, Saikat Das, Sheldon, Frederick T., Sajjan Shiva, Frederick T. Sheldon, Yacine Chakhchoukh, Mohammad Ashrafuzzaman, Das, Saikat, Shiva, Sajjan   +9 more
core   +1 more source

Gestational Hypoxia Disrupts Medial Ganglionic Eminence Progenitor Dynamics and Interneuron Development in Schizophrenia

Advanced Science, EarlyView.
FES‐derived MGE spheroids exhibit progenitor‐stage alterations in developmental trajectory and hypoxia‐responsive transcriptional programs, followed by functional disruption. Gestational hypoxia recapitulates impaired progenitor proliferation, shortened cell‐cycle progression, interneuron developmental abnormalities, and schizophrenia‐like behaviors in
Peiyan Ni, Qiancheng Zhang, Youhui Jiang, Huiying Yao, Chuqing Zhou, Xiaoyi Tian, Shiyingnan Gao, Jun Zhao, Xinyi Ren, Naxin Xu, Mengshan Fu, Liansheng Zhao, Xueyu Qi, Xueli Yu, Wanjun Guo, Sangmi Chung, Fan Guo, Tao Li   +17 more
wiley   +1 more source

A Novel Pak1 Activator Ameliorates ER Stress for HFpEF Therapy

Advanced Science, EarlyView.
Chronic metabolic stress is a major contributor to HFpEF progression. Under prolonged metabolic stress, Pak1 activity becomes impaired, contributing to disrupted ER proteostasis, cardiomyocyte apoptosis, fibrosis, and diastolic dysfunction. Mechanistically, Pak1 overexpression activates the ERK1/2–MNK1–eIF4E signaling axis, promotes translational ...
Honglin Xu, Hongyuan Zhang, Tayyiba Azam, Susanne S. Hille, Yingjuan Liu, Min Zi, Jiaqing Lang, He Yu, Yujia Cao, Bernard D. Keavney, Tamer M. A. Mohamed, Jessica M. Miller, Riham R. E. Abouleisa, Ming Xu, Elizabeth J. Cartwright, Oliver J. Müller, Ming Lei, Xin Wang   +17 more
wiley   +1 more source

Resilient distributed resource allocation algorithm under false data injection attacks

, 2022
A resilient distributed algorithm is proposed to solve the distributed resource allocation problem of a first-order nonlinear multi-agent system who is subject to false data injection (FDI) attacks. An intelligent attacker injects false data into agents'
Nan, Xinyuan, Gao, Binpeng, Cai, Xin
core  

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Blood Cell‐Camouflaged Liquid Metal Nanoconjugates Orchestrate Treg Depletion and STING‐Amplified Photothermal Immunity for Metastatic Triple‐Negative Breast Cancer Therapy

Advanced Science, EarlyView.
Whole‐blood biomimetic engineering transforms liquid metal nanoparticles into a tripartite immunotherapeutic platform that orchestrates regulatory T‐cell depletion, photothermal‐induced immunogenic cell death, and activation of the stimulator of interferon genes pathway.
Nina Sang, Eijiro Miyako
wiley   +1 more source

False Image Injection Prevention Using iChain

Applied Sciences, 2019
The advances in information and communication technology are consistently beneficial for the healthcare sector. A trend in the healthcare sector is the progressive shift in how data are acquired and the storage of such data in different facilities, such ...
Mohiuddin Ahmed
doaj   +1 more source