Results 161 to 170 of about 24,681,994 (291)
Abstract Efforts to use transcriptomics for toxicity testing have classically relied on the assumption that chemicals consistently produce characteristic transcriptomic signatures that are reflective of their mechanism of action. However, the degree to which transcriptomic responses are conserved across different test methodologies has seldom been ...
Paul Béziers +10 more
wiley +1 more source
Triggered Calcium Lightning Programs Cochlear Development
Summary: Before the onset of hearing, the developing inner ear generates spontaneous calcium signals that are thought to guide maturation. In this study, we discovered a rapid and widespread calcium flash—dubbed “Ca2+ lightning”—originating from supporting cells beneath the sensory hair cells, which triggers coordinated calcium waves across the entire ...
Qiang Ma +13 more
wiley +1 more source
Multi‐omics–driven precision medicine
Multi‐omics‐driven precision medicine (MODPM) provides a multiscale, continuously learnable framework that integrates genomics, epigenomics, transcriptomics, proteomics, metabolomics, microbiome profiles, and clinical data. Powered by artificial intelligence and foundation models, MODPM enables cross‐modal representation learning, contextual modeling ...
Huibo Li +20 more
wiley +1 more source
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid +4 more
wiley +1 more source
A Hybrid Deep Autoencoders and Random Forest Framework for False Data Injection Attack Detection in Industrial Internet of Things Networks. [PDF]
Albarrak AM +3 more
europepmc +1 more source
We detect the risk factors and image characteristics of incidentally detected IAAD. Independent risk factors of IAAD included fatty liver and smoking. In the ultrasound findings of IAAD, an intimal flap was frequently observed. In the CT scan, displacement of intimal calcifications was frequently observed. For suspected IAAD, the abdominal aorta should
Hiromasa Tsubouchi +15 more
wiley +1 more source
Minimizing Risk of Load Redistribution Attacks on Electric Grids in the Presence of Insider Threats. [PDF]
Zhan L, Mehrani S, Xie C, Dehghanian P.
europepmc +1 more source
ABSTRACT The ability of organisms to effectively respond to challenges is critical for survival. We investigated how an acute stressor affected corticosterone, mitochondrial function, and DNA oxidative damage in a wild population of Leach's storm‐petrels (Hydrobates leucorhous).
Kayla E. Lichtner +10 more
wiley +1 more source
Patient-Specific Spatio-Temporal False Data Injection Attack Detection for IoMT Using a Graph-GRU Digital Twin and Kalman Innovation Features. [PDF]
Alkhammash EH +3 more
europepmc +1 more source
The aim of this study was to explore radiography students' knowledge, attitudes, and practice (KAP) relating to infection prevention and control (IPC) in the use of contrast media injectors in the computed tomography (CT) setting. Radiography students demonstrate varied comprehension of IPC regarding contrast media equipment within CT environment, and ...
Dania Abu Awwad +4 more
wiley +1 more source

