Results 201 to 210 of about 46,655 (287)

Family Media Practices in a Post‐Pandemic Future: Conversations From a Transglobal Research Project

open access: yesChildren &Society, EarlyView.
ABSTRACT This article is co‐written by a team of researchers who worked together during the pandemic to conduct parallel research projects in their home countries, collectively referencing the project as Children, Media and Pandemic Parenting. Our article consists of a series of curated thought pieces, drawing on interviews with parents in Australia ...
Natalie Coulter   +7 more
wiley   +1 more source

PIK‐III‐Mediated Elevation of Thiamine Re‐Sensitises Renal Cell Carcinoma to Cuproptosis via Activating PDHA1

open access: yesCell Proliferation, EarlyView.
PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie   +8 more
wiley   +1 more source

Navigating the dual burden of type 1 diabetes and mental illness: A phenomenological study

open access: yesDiabetic Medicine, EarlyView.
Abstract Objective Despite high burdens of mental illness among people with type 1 diabetes (T1D), little is known about how affected individuals experience this dual disease burden. This qualitative study aimed to address this gap. Research Design and Methods Five online focus groups were conducted with 21 adults with T1D and a history of mental ...
Zach W. Cooper   +3 more
wiley   +1 more source

Early Clinical Experiences for Dental Students Using Near Peer Assisted Learning (NPAL)

open access: yesEuropean Journal of Dental Education, EarlyView.
ABSTRACT Introduction This paper describes Doctor of Dental Surgery students' perspectives on participating in NPAL sessions at the School of Dentistry at the University of Alberta. NPAL provides early clinical experiences (ECE) for junior students (mentees) assisted by senior students (mentors).
Anthea Senior   +4 more
wiley   +1 more source

Daily intermittent fasting is an effective multiscale treatment in preclinical models of absence epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Absence epilepsy is characterized by brief but frequent seizures with loss of consciousness. Existing treatments, which come with heavy side effects, are only partially effective and do not address the associated comorbidities, including cognitive and social deficits.
Coline Rulhe   +9 more
wiley   +1 more source

Extracellular vesicle proteomics identifies novel blood biomarkers for the early diagnosis of status epilepticus

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to identify novel blood‐based biomarkers associated with the early diagnosis of status epilepticus (SE) by exploring proteomic alterations in plasma extracellular vesicles (EVs). Methods We conducted an observational and prospective study in a two‐phase design: a discovery proteomic analysis of plasma EVs ...
Estevo Santamarina   +11 more
wiley   +1 more source

Conditional deletion of the multiple sclerosis susceptibility gene ATXN1 identifies cell‐autonomous effects in the B‐cell compartment

open access: yesThe FEBS Journal, EarlyView.
Ataxin‐1 is a polyglutamine protein associated with the etiology of spinocerebellar ataxia type 1 (SCA1) that has been recently found implicated in the risk of developing the autoimmune disorder multiple sclerosis (MS). Here, we took a conditional knockout approach to ablate ataxin‐1 exclusively in the B‐cell compartment and we found that this protein ...
Jonathan Jacob Carver   +3 more
wiley   +1 more source

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