Results 171 to 180 of about 537,139 (296)

Factors associated with false positive results in serological testing for syphilis using EIA among children. [PDF]

Front Pediatr
Liu J, Chen Q, Zhao G, Fan X, Wang W.
europepmc   +1 more source

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Development and Validation of a Multigene Panel for Pharmacogenomics Testing Using Next-Generation Sequencing for Routine Clinical Practice. [PDF]

Clin Transl Sci
Hongkaew Y, Kunadirek P, Sangtian M, Pateetin P, Bunlungsup S, Panmontha W, Kawprasertsri S, Khunlertkit T.   +7 more
europepmc   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Patch Test Preparations: Basis and State-of-the-Art Modern Diagnostic Tools for Contact Allergy. [PDF]

J Clin Med
Zimmer J, Neimanis S, Schmidt S, Schubert S, Mahler V.   +4 more
europepmc   +1 more source

Targeting the PDK1/c‐Myc/SOX10 Signaling in Oligodendrocytes Alleviates Neuropathic Pain

Advanced Science, EarlyView.
This work reveals that oligodendrocyte homeostasis, mediated by PDK1, is a critical determinant of neuropathic pain (NPP) pathogenesis. Disruption of PDK1 in oligodendrocytes impairs SOX10‐dependent myelination programs through c‐Myc accumulation, leading to disrupted myelination and the pathophysiology of NPP.
Pingping Qiao, Lifang Guo, Guochao Yang, Chaoli Huang, He Wang, Jian‐Jun Yang, Guiquan Chen, Yimin Hu   +7 more
wiley   +1 more source

A multi-way SMILES-based hypergraph inference network for metabolic model reconstruction. [PDF]

Commun Biol
Zhao Y, Chen Y, Yu Y, Liu X, Du J, Wen J, Sun Q, Wang R, Chen C.   +8 more
europepmc   +1 more source

Oral Streptococcus salivarius Couples Neutrophil IRGM1 Signaling to NET Formation and Colorectal Cancer Metastasis

Advanced Science, EarlyView.
The oral bacterium Streptococcus salivarius promotes colorectal cancer metastasis by inducing neutrophil extracellular trap (NET) formation. Mechanistically, IRGM1–IQGAP1 interaction activates Wnt5a–PI3K/AKT signaling in neutrophils, driving NET‐mediated tumor progression.
Fengyi Liu, Yuan Wang, Hengxuan Cai, Qianwen Yue, Xueli Liu, Xuanwen Bao, Zeng Wang, Xuehan Li, Lai Wei, Zhihua Zhang, Fan Xing, Yi Xu, Xianjun Li, Wei Xu   +13 more
wiley   +1 more source

Intervening and reducing sharing of false cancer treatments on social media: Online experiment. [PDF]

PLoS One
Lazard AJ, Lake S, Queen TL, Avendaño-Galdamez M, Babwah Brennen S, Varma T, Tan HJ, Charlot M, Dasgupta N.   +8 more
europepmc   +1 more source

Latex allergy: a challenge for anaesthetists [PDF]

, 2006
Demaegd, J, Herregods, Luc, Soetens, F
core   +1 more source