Results 181 to 190 of about 564,270 (247)

A NeuroD1 AAV‐Based Gene Therapy for Functional Brain Repair in Alzheimer's Disease‐Like Non‐Human Primate Model

Advanced Science, EarlyView.
This study tests NeuroD1 AAV‐based gene therapy in a non‐human primate Alzheimer's disease model. The therapy prevents neuronal damage, inhibits hippocampal atrophy, and reduces neuroinflammation. It also repairs vascular and blood‐brain barrier damage, restores cerebrospinal fluid biomarkers, enhances hippocampal glucose metabolism, and improves ...
Zhouquan Jiang, Yongpeng Qin, Bin Luo, Fan Bai, Jiangyue Liu, Long Ma, Shu He, Rongjie Chen, Yuchen Wang, Shanggong Liu, Ying Sun, Yi Chen, Shuo Zhang, Jiaqi Liang, Feng Liao, Huiyi Wei, Junjie Wei, Lu Wang, Hao Xu, Zheng Wu, Gong Chen, Wenliang Lei   +21 more
wiley   +1 more source

Efflux pump knockout minimizes crosstalk and boosts response in transcription factor-based biosensors. [PDF]

J Biol Eng
Lee J, Yoo BH, Jeon E, Kong H, Rha E, Shin J, Lee H, Kim H, Lee DH, Kwon KK, Lee SG.   +10 more
europepmc   +1 more source

False positive Widal reaction in malaria.

Indian pediatrics, 1994
J R, Sharma, I B, Parmar, S J, Sharma, A, Kesavan   +3 more
openaire   +1 more source

Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome

Advanced Science, EarlyView.
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang, Siqi Guo, Jing Li, Qianqian Huang, Jing Ning, Binbin Xia, Xun Lv, Xiang Liu, Zeyu Gao, Jine Li, Longchao Liu, Moshi Song, Jun Wang   +12 more
wiley   +1 more source

Self-supervised domain adaptation of protein language model based solely on positive enzyme-reaction pairs. [PDF]

Comput Struct Biotechnol J
Okuno T, Ono N, Altaf-Ul-Amin M, Kanaya S.   +3 more
europepmc   +1 more source

[False-positive reactions of Wassermann].

Vestnik dermatologii i venerologii, 2002
openaire   +1 more source

Drug Reaction with Eosinophilia and Systemic Symptoms in the Electronic Medical Record.

Int Arch Allergy Immunol
Jiang M, Lam L, Kovoor J, Inglis JM, Shakib S, Yuson C, Ali SB, Bacchi S, Kern JS, Sidhu S, Smith W.   +10 more
europepmc   +1 more source

Perioperative anaphylaxis due to intravenous tranexamic acid following cutaneous exposure. [PDF]

JA Clin Rep
Amano Y, Tamura T, Konishi Y, Somura Y, Akiyama K.   +4 more
europepmc   +1 more source

Basophil Activation Test as Biomarker of Severity and Threshold of Allergic Reactions to Cow's Milk During Oral Food Challenges. [PDF]

Allergy
Boyd H, Bartha I, Foong RX, Krawiec M, Marques-Mejias A, Marshall HF, Radulovic S, Harrison F, Antoneria G, Jama Z, Kwok M, Pietraszewicz E, Eghleilib M, Ricci C, Marrs T, Lack G, Du Toit G, Santos AF.   +17 more
europepmc   +1 more source

Lyophilised colourimetric LAMP for visual readout with dual colour indicators.

Analyst
Malpartida-Cardenas K, Stringer OW, Cavuto ML, Holmes A, Rodriguez-Manzano J.   +4 more
europepmc   +1 more source