Results 91 to 100 of about 1,640,499 (279)

Time‐restricted feeding prior to Mycobacterium tuberculosis infection reduces tissue CD4+ T cells with limited impact on bacterial clearance

FEBS Open Bio, EarlyView.
Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta, Nidhi Yadav, Subhasmita Das, R. Rajendra Kumar Reddy, Nupur Sharma, Amol Ratnakar Suryawanshi, Jaswinder Singh Maras, Ranjan Kumar Nanda   +7 more
wiley   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

What Do Executive Factors Contribute to the Failure on False Belief Tasks by Children with Autism? [PDF]

, 1999
As children with autism have pervasive executive difficulties it is necessary to determine whether these contribute to their often-reported failure on the false belief task. Failure on this task is frequently taken to diagnose the lack of a ``theory of
Russell, J., Hill, Elisabeth L., Saltmarsh, R.   +2 more
core   +1 more source

Space-Borne SAR High-Resolution Inshore Ship Target Identification Based on a YOLO Recognition and Correction Approach

IEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing
High-resolution space-borne synthetic aperture radar (SAR) images are important sources of information for marine monitoring and target recognition. For inshore port scenes, there is a wide variety of ship targets; moreover, as the scattering intensity ...
Yongchen Pan, Hongcheng Zeng, Yingjie Zhou, Wei Yang, Yamin Wang, Xinwei An, Can Su, Wei Xiong, Wei Liu   +8 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Adaptive detection of distributed targets in compound-Gaussian noise without secondary data: A Bayesian approach [PDF]

, 2011
In this paper, we deal with the problem of adaptive detection of distributed targets embedded in colored noise modeled in terms of a compound-Gaussian process and without assuming that a set of secondary data is available.The covariance matrices of the ...
Bandiera, Francesco, Giuseppe Ricci, Ricci, Giuseppe, O. Besson, Besson, Olivier, Olivier Besson, Francesco Bandiera   +6 more
core   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Deception Velocity-Based Method to Discriminate Physical Targets and Active False Targets in a Multistatic Radar System

Remote Sensing
Due to the silent operation of the receiver station in a multistatic radar system, it is difficult for the jammer to generate the cooperative active deception target for the multistatic radar system.
Qiang Li, Yumei Guo, Peng Zhang, Hong Xu, Linrang Zhang, Zhanye Chen, Yan Huang   +6 more
doaj   +1 more source