Results 141 to 150 of about 2,525 (238)

The Origins of Ploem's Filter Cube: A Pandora's Box

Journal of Microscopy, EarlyView.
Abstract Ploem's filter cube, central to modern epifluorescence microscopy, integrates three matched optical components: an excitation filter, an emission filter, and a dichroic mirror. Together, these elements enable the separation of excitation and emission light paths, producing high‐contrast fluorescence images.
Jack Gordon, Kaleah Balcomb, Vinod Maseedupally, Maitreyee Roy   +3 more
wiley   +1 more source

Functional morphology and biomechanics of the locomotor apparatus in the large Late Triassic carnivore Postosuchus kirkpatricki (Archosauria: Rauisuchidae)

Journal of Anatomy, EarlyView.
A three‐dimensional model is used to analyze the locomotor biomechanics of the large Late Triassic archosaurian reptile Postosuchus kirkpatricki. The study finds that it is more uncertain than previously concluded whether it was quadrupedal or bipedal, and plantigrade or digitigrade, but it clearly had locomotor specializations including large hindlimb
John R. Hutchinson, Emily Faughey, Matthew Humpage, Tristan Dupuis, Oliver E. Demuth, Romain Pintore, Francois Clarac   +6 more
wiley   +1 more source

Layer‐by‐layer soft‐tissue effects on flexion–extension‐dominant passive ex vivo limb joint ROM in quadrupedal mammals: An anatomical contribution to a morphofunctional framework

Journal of Anatomy, EarlyView.
Layer‐by‐layer passive ex vivo assessment of flexion–extension‐dominant limb joint ROM across rabbit, pudu deer, chilla fox and pig revealed joint‐, tissue‐ and taxon‐specific responses to progressive tissue removal. Proximal joints often showed increasing ROM, whereas distal joints often showed non‐monotonic responses.
Paul Medina‐González, Valentina Bernal‐Fernández, Rodrigo Arancibia‐Müller, Pedro Aburto‐Valdebenito, Marcelo Gómez‐Jaramillo   +4 more
wiley   +1 more source

Combatting Substandard and Falsified Medicines: Public Awareness and Identification of Counterfeit Medications. [PDF]

Front Public Health, 2021
El-Dahiyat F, Fahelelbom KMS, Fahelelbom KMS, Jairoun AA, Al-Hemyari SS.   +4 more
europepmc   +1 more source

Moral hazard on the ACA exchanges: Evidence from a cost‐sharing subsidy discontinuity

Journal of Risk and Insurance, EarlyView.
Abstract This paper examines the moral hazard effects of cost‐sharing subsidies on the Affordable Care Act's Health Insurance Exchanges. Exploiting a sharp discontinuity in subsidy generosity at 150% of the federal poverty level, we compare healthcare spending for individuals just above and below this threshold using a regression discontinuity design ...
Cameron M. Ellis, Meghan I. Esson, Eli Liebman   +2 more
wiley   +1 more source

Target Trial Emulation in Observational Research—Strengths, Limitations, and Methodological Considerations

Journal of Periodontal Research, EarlyView.
The target trial framework is a pragmatic roadmap for observational causal inference that clarifies questions, mitigates time‐related bias, and improves interpretability while acknowledging limits. With transparent protocols, appropriate methods, and suitable data, it can complement randomized trials and inform practice and policy.
Sebastian‐Edgar Baumeister, Ignacio Leiva‐Escobar, Ryan T. Demmer, Panos N. Papapanou, Thomas Kocher, Birte Holtfreter, Michael Nolde   +6 more
wiley   +1 more source

The urgent need for African research collaboration on medicine quality

Nature Communications
Substandard and falsified medicines threaten African health systems, yet research on this crisis is fragmented and concentrated in few countries, predominantly led by Global North institutions.
Fanqi Zeng, Simon Mariwah, Gerry Mshana, Daniel Amoako-Sakyi, Heather Hamill   +4 more
doaj   +1 more source

Surveillance for substandard and falsified medicines by local faith-based organizations in 13 low- and middle-income countries using the GPHF Minilab. [PDF]

Sci Rep, 2022
Gnegel G, Häfele-Abah C, Neci R, Difäm-EPN Minilab Network, Heide L.   +4 more
europepmc   +1 more source

Causal Inference in Clinical Research: A Primer

Journal of Periodontal Research, EarlyView.
Causal inference helps researchers move beyond describing associations to answering the question: what would happen if an exposure were changed? This article provides an intuitive overview for applied researchers. ABSTRACT The study of causal relationships is central to scientific inquiry. Understanding what disease is, why it arises, and how it can be
Nasir Z. Bashir, Moritz Kebschull, Stephen Burgess, Gustavo G. Nascimento   +3 more
wiley   +1 more source

Survey of workflow and cost implications of decommissioning regarding the Falsified Medicines Directive in Hungarian hospital pharmacies. [PDF]

BMJ Open, 2021
Vajda P, Richter K, Bodrogi Z, Vida RG, Botz L, Kovács S, Zemplényi A, Bella R, Fittler A.   +8 more
europepmc   +1 more source