Results 61 to 70 of about 172,793 (249)

FALSIFICATION OF MEDICINES AND DISTRIBUTION OF FALSIFIED MEDICINES IN UKRAINE: CRIMINALISTIC MEANS OF DETECTION AND COUNTERACTION

Wiadomości Lekarskie, 2021
The aim: To formulate criminalistic recommendations to increase the effectiveness of combating falsification and contribution of falsified medicines. To accomplish analyze of the current state and trends in combating this criminal offense, to create the basis of criminalistic characteristics and methods of their investigation, taking into account the ...
Viktor M, Shevchuk, Ihor V, Parfylo, Mykyta O, Sokolenko   +2 more
openaire   +2 more sources

Investor Perceptions of Climate Policy: Insights From the US Inflation Reduction Act

Business Strategy and the Environment, EarlyView.
ABSTRACT This paper provides the first event study evidence on how the Inflation Reduction Act's (IRA) dedicated climate provisions reshaped equity valuations in the US carbon‐intensive sectors. Focusing on environmentally sensitive industries (ESI), we analyze cumulative abnormal returns around the four key IRA milestones in 2022–2023.
Laura Ferraro, Arati Kale, Devendra Kale, Franco Ernesto Rubino   +3 more
wiley   +1 more source

Substandard, falsified and unregistered medicines in Latin America, 2017-2018

Revista Panamericana de Salud Pública, 2020
Objective. To assess all the incidents of substandard, falsified and unregistered medicines in 2017 and 2018 in Latin America, determining the types of products affected, stages of the supply chain in which incidents were detected, quality deviations ...
Robin Rojas-Cortés
doaj   +1 more source

Weather Action: A Study on the Industry Peer Effects of Corporate Climate Risk Information Disclosure

Business Strategy and the Environment, EarlyView.
ABSTRACT Global climate change has elevated the strategic importance of corporate climate risk disclosure, yet the role of industry peer effects in shaping such disclosure remains underexplored. Grounded in social learning theory, this study proposes an “observation–imitation–reinforcement” framework and empirically tests it using panel data on Chinese
Huer Shuang, Shenghua Lou, Renjie Luo, Jiajia Luo   +3 more
wiley   +1 more source

What's in a Word? Falsified/Counterfeit/Fake Medicines - The Definitions Debate

Medicine Access @ Point of Care, 2017
There is a rising tide of criminal activity to manufacture and distribute falsified, counterfeit, or fake medicines. The exact size of this problem is unknown but estimates vary from US$75 billion to US$200 billion per year, and evidence clearly ...
Mike Isles
doaj   +1 more source

The EU Falsified Medicines Directive: Key Implications for Dispensers [PDF]

Medicine Access @ Point of Care, 2017
The EU Falsified Medicines Directive (FMD) mandates the serialisation of prescription-only medicines using a two-dimensional (2D) barcode by pharmaceutical companies and the systematic verification of this 2D barcode in pharmacies. This European directive has ramifications for many stakeholders, including market authorization holders, wholesalers ...
openaire   +3 more sources

How to achieve international action on falsified and substandard medicines [PDF]

BMJ, 2012
Substandard and falsified medicines kill patients, yet progress on the twin challenges of safeguarding the quality of genuine medicine and criminalising falsified ones has been held back by controversy over intellectual property rights and confusion over terms.
Attaran, A, Barry, D, Basheer, S, Bate, R, Benton, D, Chauvin, J, Garrett, L, Kickbusch, I, Kohler, J, Midha, K, Newton, P, Nishtar, S, Orhii, P, McKee, M   +13 more
openaire   +4 more sources

From Biological Mechanisms to Causal Inference: Quantitative Systems Pharmacology and Causal Frameworks in Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Digital patients and in silico clinical trials offer new opportunities to advance pharmacological research, clinical development, and regulatory decision‐making by enabling the simulation of treatment effects prior to testing in patients. Among the most promising of these opportunities is the combined use of quantitative systems pharmacology (QSP) and ...
Thomas Klabunde, Ramon Hernandez, Piet H. van der Graaf, Tommaso Andreani   +3 more
wiley   +1 more source

Metabolomic Study of 7-Ethyl-9-(N-methyl)aminomethyl-10-hydroxycamptothecin Derivative (NMe)—The Chemotherapeutic Drug Candidate Versus Irinotecan (IR) on a Mouse Model

Metabolites
Background: In this study, we aimed to compare metabolomic profiles, biodistribution, and detoxification patterns of the novel SN-38 derivative NMe with irinotecan (IR), and to identify NMe-specific metabolites to evaluate its preclinical pharmacokinetic
Piotr Surynt, Beata Naumczuk, Magdalena Popławska, Magdalena Urbanowicz, Katarzyna Unrug-Bielawska, Magdalena Cybulska-Lubak, Zuzanna Sadowska-Markiewicz, Jerzy Sitkowski, Elżbieta Bednarek, Natalia Zeber-Lubecka, Lech Kozerski, Michał Mikula, Jerzy Ostrowski   +12 more
doaj   +1 more source

A cross-sectional analysis of falsified, counterfeit and substandard medicines in a low-middle income country

BMC Public Health, 2020
Background High prevalence of falsified, counterfeit and substandard medicines pose a threat to public health and treatment failure. This study aimed to investigate the quality of selected essential medicines available in Mongolia.
Daariimaa Khurelbat, Gereltuya Dorj, Bruce Sunderland, Tsetsegmaa Sanjjav, Enkhtuul Bayarsaikhan, Davaadagva Damdinjav, Gantuya Dorj, Altantuya Jigjidsuren, Oyun Lkhagvasuren, Baasandorj Erdenetsetseg   +9 more
doaj   +1 more source