Results 91 to 100 of about 34,596 (267)

Pyrin dephosphorylation is sufficient to trigger inflammasome activation in familial Mediterranean fever patients

open access: yesEMBO Molecular Medicine, 2019
Familial Mediterranean fever (FMF) is the most frequent hereditary systemic autoinflammatory syndrome. FMF is usually caused by biallelic mutations in the MEFV gene, encoding Pyrin.
F. Magnotti   +17 more
semanticscholar   +1 more source

Comorbidities and Healthcare Utilization in 4197 Patients With Prurigo Nodularis in Israel: A Cross‐Sectional Population‐Based Analysis

open access: yesInternational Journal of Dermatology, EarlyView.
ABSTRACT Background Prurigo nodularis patients face a significant burden of comorbidities, necessitating a comprehensive approach to care. We aimed to explore the association between prurigo nodularis, its comorbid conditions, and healthcare usage patterns.
Yuliya Valdman‐Grinshpoun   +4 more
wiley   +1 more source

Familial Mediterranean Fever: Assessing the Overall Clinical Impact and Formulating Treatment Plans

open access: yesMediterranean Journal of Hematology and Infectious Diseases, 2019
Recurrent self-limited attacks of fever and short-lived inflammation in the serosal membranes, joints, and skin are the leading features of familial Mediterranean fever (FMF), the most common autoinflammatory disorder in the world, transmitted as ...
D. Rigante, R. Manna
semanticscholar   +1 more source

The Role of NLRP1, AIM2 and MEFV Inflammasomes in the High‐Intensity Interval Training of Individuals With Obesity

open access: yesImmunology, EarlyView.
This study shows that 8 weeks of high‐intensity interval training (HIIT) modulate inflammasome‐related gene expression in individuals with obesity. HIIT increased AIM2, MEFV, CARD16 and CARD18 expression, with CARD16 upregulation supporting reduced inflammation through inhibition of caspase‐1 activation and lower IL‐1β levels.
Ana Luíza Pereira Assunção Silveira   +8 more
wiley   +1 more source

Future perspective for diagnosis in autoimmune diseases [PDF]

open access: yes, 2009
Human beings have taken successive approaches for the understanding and management of diseases. Initially brewed in supernatural concepts and mystical procedures, a vigorous scientific approach has emerged on the grounds of fundamental disciplines such ...
Andrade, Luiz Eduardo Coelho
core   +3 more sources

TNF Inhibitor Therapy in Corticosteroid‐Resistant or ‐Dependent Pediatric Neutrophilic Dermatosis

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Neutrophilic dermatoses are rare in children. Systemic corticosteroids are the first‐line treatment, but guidelines for second‐line therapies are lacking. We report five cases of children with systemic steroid‐resistant/dependent neutrophilic dermatoses, successfully treated with tumor necrosis factor inhibitors.
Laure Chêne   +7 more
wiley   +1 more source

Familial Mediterranean fever in northwest of Iran (Ardabil): The first global report from Iran [PDF]

open access: yes
Familial Mediterranean fever (FMF), which is the prototype of the hereditary periodic fever syndromes, is common in the countries around the Mediterranean Sea. Considering its geographical position in the northwest of Iran, with its population of Turkish
امامی, دینا   +10 more
core  

Ursodeoxycholic acid for treatment of cholestasis in patients with hepatic amyloidosis [PDF]

open access: yes, 2009
Background. Amyloidosis represents a group of different diseases characterized by extracellular accumulation of pathologic fibrillar proteins in various tissues and organs.
Akoglu Bora   +3 more
core   +1 more source

Association of Vasculitis and Familial Mediterranean Fever

open access: yesFrontiers in Immunology, 2019
Certain types of vasculitis occur more frequently and present differently in patients with familial Mediterranean fever (FMF). We assessed the characteristics of patients with FMF and systemic vasculitis through a systematic review of the literature ...
S. Abbara   +4 more
semanticscholar   +1 more source

Predictors of persistent inflammation in familial Mediterranean fever and association with damage.

open access: yesRheumatology, 2020
OBJECTIVE Persistent inflammation is an insidious and less studied feature of FMF. We investigated clinical determinants of persistent inflammation and its associations with individual damage items. METHODS This is a cross-sectional analysis of 917 FMF
H. Babaoğlu   +17 more
semanticscholar   +1 more source

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