Results 51 to 60 of about 8,225 (170)

Familial mediterranean fever: clinical case

Клиническая практика, 2019
Background. Familial Mediterranean fever (FMF) is the brightest exponent of autoinflammatory diseases. FMF usually occurs to people of Mediterranean origin (Jews, Armenians, Azerbaijanis, Arabs, Kurds, Greeks, Turks and Italians).
Roman S. Saykovskiy, S. V. Sadovnikova
doaj   +1 more source

TNF Inhibitor Therapy in Corticosteroid‐Resistant or ‐Dependent Pediatric Neutrophilic Dermatosis

Pediatric Dermatology, EarlyView.
ABSTRACT Neutrophilic dermatoses are rare in children. Systemic corticosteroids are the first‐line treatment, but guidelines for second‐line therapies are lacking. We report five cases of children with systemic steroid‐resistant/dependent neutrophilic dermatoses, successfully treated with tumor necrosis factor inhibitors.
Laure Chêne, Thomas Hubiche, Jean‐Marie De Guillebon, Maella Severino‐Freire, Emmanuelle Bourrat, Sébastien Barbarot, Alice Phan, Christine Chiaverini   +7 more
wiley   +1 more source

HHV‐8/KSHV in Solid Organ Transplantation: Current Gaps of Knowledge and Future Directions

Transplant Infectious Disease, EarlyView.
Risk mitigation strategies, including donors/recipients screening, DNAemia monitoring in recipients at risk, CNI‐to‐mTOR inhibitors switch, antivirals, and rituximab for KICS, may mitigate the impact of HHV‐8/KSHV infection in SOT. This review provides an update on KICS, identifies research gaps, and summarizes advances in screening and management ...
Alessandra Mularoni, Andrea Cona, Malgorzata Mikulska, Francesca Pecoraro, Carlotta Piazza, Elda De Vita, Giada Pietrosi, Matteo Bulati, Tiziana Lazzarotto, Mario Luppi   +9 more
wiley   +1 more source

Safety, tolerability and pharmacokinetics of DNDI‐6148, a novel agent for leishmaniasis: A randomized, controlled, single ascending dose study in healthy participants

British Journal of Clinical Pharmacology, Volume 92, Issue 4, Page 1087-1097, April 2026.
Aim The benzoxaborole derivative DNDI‐6148 is an antiparasitic agent with activity against multiple Leishmania protozoan species, including L. infantum and L. donovani, which cause visceral leishmaniasis. We investigated the safety, tolerability and pharmacokinetics of single oral doses of DNDI‐6148 in a randomized, parallel‐group, placebo‐controlled ...
Jean‐Yves Gillon, Sophie Delhomme, Delphine Launay, Séverine Blesson, Stéphanie Braillard, Pegah Maghdooni, Frauke Assmus, Richard Hoglund, Joel Tarning, Sabrina Loyau, Byron Arana, Mathilde Latreille‐Barbier, Yves Donazzolo   +12 more
wiley   +1 more source

Adalimumab‐responsive Monogenic Inflammatory Bowel Disease With Pseudopolyposis Characteristic of TGFBR2 Variant in Loeys‐Dietz Syndrome

DEN Open, Volume 6, Issue 1, April 2026.
ABSTRACT Loeys‐Dietz syndrome (LDS) is an autosomal dominant connective tissue disorder caused by pathogenic variants in TGFBR1 or TGFBR2. It is characterized by vascular fragility, skeletal abnormalities, and predisposition to allergic and inflammatory conditions, including monogenic inflammatory bowel disease (IBD).
Tomomitsu Sado, Satoshi Ukai, Shingo Kurasawa, Yosuke Kono, Norio Hasuda, Mai Iwaya, Takaya Nakane, Tomomi Yamaguchi, Tomoki Kosho, Yoshiko Nakayama   +9 more
wiley   +1 more source

Antimicrobial Effect of Spices and Their Phytochemicals: A Novel Approach to Overcoming Antibiotic Resistance

MedComm, Volume 7, Issue 4, April 2026.
This graphical abstract shows the antibacterial potential of phytochemicals from 15 spices, showcasing key compounds, their extraction methods, and mechanisms of action. It highlights membrane disruption, ROS generation, enzyme inhibition, and biofilm prevention as core antibacterial pathways.
Hettiyahandi Binodh De Silva, Yanqi Dai, Shervanthi Homer‐Vanniasinkam, Mohan Edirisinghe   +3 more
wiley   +1 more source

Comorbidities and Healthcare Utilization in 4197 Patients With Prurigo Nodularis in Israel: A Cross‐Sectional Population‐Based Analysis

International Journal of Dermatology, Volume 65, Issue 4, Page 763-773, April 2026.
ABSTRACT Background Prurigo nodularis patients face a significant burden of comorbidities, necessitating a comprehensive approach to care. We aimed to explore the association between prurigo nodularis, its comorbid conditions, and healthcare usage patterns.
Yuliya Valdman‐Grinshpoun, Andrea Zaga, Arnon Dov Cohen, Yochai Schonmann, Tali Czarnowicki   +4 more
wiley   +1 more source

Familial Mediterranean Fever: an unusual cause of liver disease

Italian Journal of Pediatrics, 2019
Background Familial Mediterranean Fever is an autoinflammatory disease typically expressed with recurrent attacks of fever, serositis, aphthous stomatitis, rash. Only a few reports describe the association with hepatic involvement.
Maria Cristina Maggio, Maria Castiglia, Giovanni Corsello   +2 more
doaj   +1 more source

The usefulness and reliability of English-language YouTube videos as a source of knowledge for patients with familial Mediterranean fever [PDF]

PeerJ
Background/Objectives YouTube is increasingly being used as an educational tool and is a substantial source of information. This study aimed to assess the quality of the most viewed YouTube videos pertaining to familial Mediterranean fever (FMF). Methods
Belkıs Nihan Coşkun, Burcu Yagiz, Esra Giounous Chalil, Ediz Dalkılıç, Yavuz Pehlivan   +4 more
doaj   +2 more sources

Canakinumab as rescue therapy in familial Mediterranean fever refractory to conventional treatment

Drug Design, Development and Therapy, 2015
Mirella Alpa, Dario Roccatello Centro di Ricerche di Immunopatologia e Documentazione su Malattie Rare (CMID), Struttura Complessa Direzione Universitaria di Immunologia Clinica, Università di Torino e Ospedale G Bosco, Torino, ItalyAbstract ...
Alpa M, Roccatello D
doaj