Results 111 to 120 of about 857,571 (288)

Fear of the Unknown: Familiarity and Economic Decisions [PDF]

Evidence indicates that people fear change and the unknown. We offer a model of familiarity bias in which individuals focus on adverse scenarios in evaluating defections from the status quo.
Cao, Henry, Han, Bing, Hirshleifer, David, Zhang, Harold   +3 more
core   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Unitization Based Memory Enhancement in Younger and Older Adults

Journal of Cognition
Memory for episodic associations declines with ageing due to decreased recollection abilities. Unitization—the encoding of multiple items as one integrated entity—has been shown to support familiarity-based retrieval that is independent of recollection ...
Joshua Kah Meng Khoo, Roni Tibon
doaj   +1 more source

Fragments of a larger whole: Retrieval cues constrain observed neural correlates of memory encoding [PDF]

, 2007
Laying down a new memory involves activity in a number of brain regions. Here, it is shown that the particular regions associated with successful encoding depend on the way in which memory is probed.
Otten, LJ
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

Molecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta, Yang Song, Madeleine Ndahayo, Anirudh Saxena, Theresa Guo, Dylan Z. Kelley, Jessica Gore, Andrew Hennigan, Alexa Anderson, John C. Papadimitriou, Daria A. Gaykalova   +10 more
wiley   +1 more source

The Lorentz-Dirac and Landau-Lifshitz equations from the perspective of modern renormalization theory

, 2013
This paper uses elementary techniques drawn from renormalization theory to derive the Lorentz-Dirac equation for the relativistic classical electron from the Maxwell-Lorentz equations for a classical charged particle coupled to the electromagnetic field.
Barut A. O., Charles W. Nakhleh, Rohrlich F.   +2 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

PENGARUH PRICE FAIRNESS TERHADAP BEHAVIORAL INTENTIONS DENGAN FAMILIARITY SEBAGAI VARIABEL MODERASI PADA PENGUNJUNG HOTEL NAGOYA INN KOTA SABANG [PDF]

, 2018
ABSTRAKTujuan penelitian adalah untuk mengetahui (1) mengetahui pengaruh price fairness terhadap behavioral intentions pada Hotel Nagoya Inn Kota Sabang, (2) pengaruh familiarity terhadap behavioral intentions pada Hotel Nagoya Inn Kota Sabang, (3 ...
Rizqa Nuzula
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source