Results 181 to 190 of about 71,567 (304)

Le français au Québec : représentation et conséquences pédagogiques [PDF]

, 1998
Nemni, Monique
core   +1 more source

Health literacy and loneliness among physically inactive Danes aged 18-65: a cross-sectional study. [PDF]

Front Public Health
Sarmanlu D, Heuck IR, Maindal HT, Lim MH, Ryom K.   +4 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

[Covid-19 and adolescence: Clinical findings and psychopathological thoughts about some immediate or differed impacts]. [PDF]

Neuropsychiatr Enfance Adolesc, 2023
Mille C, Boudailliez B, Garny de La Rivière S.   +2 more
europepmc   +1 more source

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source

Syndrome d’autofermentation chez une femme de 50 ans. [PDF]

CMAJ
Zewude RT, Croitoru K, Das R, Goldman B, Bogoch II.   +4 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

["I get a whole different view": Professionals experiences with family-oriented practice in addiction treatment]. [PDF]

Nordisk Alkohol Nark, 2020
Kalsås ØR, Selbekk AS, Ness O.
europepmc   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Karakteristika for familier med 4-6-årige børn, der spiser mindre end 300 gram frugt og grønt om dagen:Notat til 6 om dagen [PDF]

, 2008
Fagt, Sisse, Groth, Margit Velsing, Kørup, Karsten, Sørensen, Mette Rosenlund   +3 more
core