Results 101 to 110 of about 2,565,548 (299)

The growing effect of job demands on teacher mental health: results from a longitudinal national household panel survey

open access: yesBMC Public Health
Background Teacher mental health is an important predictor of student outcomes and teacher workforce retention, and has been declining for some years, exacerbated by the COVID-19 pandemic.
Richard W. Morris   +3 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Building happier bonds: gratitude as a mediator between dyadic coping and relationship satisfaction in romantic couples

open access: yesFrontiers in Psychology
IntroductionGratitude has been found to be relevant for relational well-being, and there has been ongoing interest in uncovering the mechanisms by which gratitude functions in interpersonal relationships.
Michelle Roth   +5 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Methodologies of Care: A Multimodal, Participatory Research Approach with Vulnerable Families Among South African Communities

open access: yesMethods and Protocols
Multimodal methods provide valuable opportunities within Participatory Action Research (PAR), to foster meaningful participation, and amplify marginalized voices.
James Reid   +6 more
doaj   +1 more source

The "Family" in Family Physician [PDF]

open access: yesThe Primary Care Companion For CNS Disorders, 2000
openaire   +2 more sources

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