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Results 111 to 120 of about 2,565,548 (299)

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source

Legislative summary (Connecticut. Dept. of Children and Families : Online)

, 2010
Annual; Harvested from the web on 12/6 ...

core +1 more source

Challenging school experiences of unavoidable absence and return for young people with chronic health conditions in English secondary schools: a qualitative, multi-informant study

Frontiers in Education
IntroductionSchool absences rates in England have remained high since the COVID-19 pandemic and reducing absence is a policy priority. Evidence shows that young people with chronic health conditions have higher school absence and worse educational ...
Lauren Herlitz +5 more
doaj +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

“That's just typical!” A qualitative video review study on the ecological validity of couples' stress conversations in the lab

Frontiers in Psychology
ObjectiveFor research on dyadic coping—how partners in intimate relationships deal with stress together—video-recorded behavioral observations in a lab are considered to be the best way to study actual coping behavior interactions.
Katharina Weitkamp, Jasmin Constam, Guy Bodenmann +2 more
doaj +1 more source

Legislative summary (Connecticut. Department of Children and Families : Online)

, 2016
Annua

core

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

FEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source

Connecticut Department of Children and Families

, 2008
Updated irregularly; Began in 2002?; Title from home page (publisher's Web site, viewed Nov. 19, 2010).; At head of title: State of Connecticut.; Harvested from the web on 1/5/11Official website of the Connecticut Department of Children and Families ...

core +1 more source

“I Could Stop and Breathe”: Early Implementation Results of a Short-Term Care Coordination Model for Children with Medical Complexity

International Journal of Integrated Care
Introduction: Children with medical complexity (CMC) are a vulnerable population with high healthcare utilisation and significant care coordination challenges.
Stephanie Hodgson +3 more
doaj +1 more source

demography
vital events
population

dyadic coping
adolescents