Results 201 to 210 of about 10,136,889 (397)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Family-level specialization in protein domain insertion architectures. [PDF]

Protein Sci
Schaeffer RD, Guo R, Zhang J, Cong Q, Grishin NV.   +4 more
europepmc   +1 more source

Evaluation of the holding families East Lancashire (pilot) project [PDF]

, 2010
Doherty, P, Foley, M, Halligan, J, Long, T, Murphy, C, Murphy, M, Yates, P   +6 more
core  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Risky families: family social environments and the mental and physical health of offspring.

Psychological bulletin, 2002
R. Repetti, Shelley E. Taylor, T. Seeman
semanticscholar   +1 more source

What Influences Speech Pathology Practice for Children with Complex Communication Needs from Multilingual Families? An Australian Perspective. [PDF]

Int J Lang Commun Disord
Skinner N, Barnes S.
europepmc   +1 more source

Risk factors associated with contraception non-use between 1995 and 2002 an analysis of the national survey of family growth, cycle 5 and cycle 6 datasets

, 2008
Lauren Robertson
openalex   +1 more source

The family in family medicine research

Academic Medicine, 1980
J, Froom, M G, Rosen
openaire   +3 more sources

The Family Doctor and the Family Nurse [PDF]

BMJ, 1964
G, SWIFT, I A, MACDOUGALL
openaire   +2 more sources

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source