Results 181 to 190 of about 3,918,732 (346)

PERCEPŢII PRIVIND ANGAJAMENTUL DE ROL ŞI CONFLICTUL MUNCĂ-FAMILIE LA ANGAJAŢII DIN REPUBLICA MOLDOVA: STUDIU EXPLORATIV

open access: yesStudia Universitatis Moldaviae: Stiinte ale Educatiei, 2017
Unul dintre conflictele motivaţionale întâlnite frecvent în mediul organizaţional este „conflictul familie-muncă”. Conflictul, în acest caz, derivă din nevoia de a integra în mod optim solicitările legate de rolul familial cu cele ale rolului profesional.
Carolina PLATON   +9 more
doaj  

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

open access: yesFEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies   +3 more
wiley   +1 more source

Examining a Comprehensive Model of Work and Family Demands, Work–Family Conflict, and Depressive Symptoms in a Sample of Correctional Supervisors

open access: green, 2019
Sara Namazi   +6 more
openalex   +2 more sources

Family Supportive Supervision Around the Globe

open access: yes, 2018
Family-supportive supervision (FSS) refers to the degree to which employees perceive their immediate supervisors as exhibiting attitudes and behaviors that are supportive of their family role demands (Hammer, Kossek, Zimmerman, & Daniels, 2007; Kossek ...
Hammer, Leslie B.   +2 more
core  

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

open access: yesFEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani   +6 more
wiley   +1 more source

A study of relationship between work-family conflict and occupational stress in police personnel

open access: yesArchives of Mental Health, 2016
Background: Both work and family are central to one's life but these roles do not always readily reconcile, in particular when workers are faced with major stressors in the work place and long working hours, such as in police service.
Ramya P Keerthi   +2 more
doaj  

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